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Acute Myelofibrosis Mimicking Multiple Bone Metastases on Tc-99m MDP Bone Imaging

1998; Lippincott Williams & Wilkins; Volume: 23; Issue: 1 Linguagem: Inglês

10.1097/00003072-199801000-00001

1536-0229

Wim J.G. Oyen, J M Raemaekers, Frans H.M. Corstens,

Bone health and treatments

Purpose Tc-99m bone scintigraphy is widely used for evaluation of osseous spread of malignant tumors. Patient A 60-year-old man had multiple areas of increased uptake on a bone scan in a pattern considered characteristic for extensive metastatic disease. However, a primary neoplasm could not be identified. Finally, acute myelofibrosis-a rare, fatal myeloproliferative syndrome-was diagnosed. Conclusion To avoid delays and extensive diagnostic procedures, acute myelofibrosis should be considered in the differential diagnosis of bone scans showing multiple hot spots. In such cases, a diagnosis can be made on an a tissue sample.