Artigo Acesso aberto Revisado por pares

Inverse electron demand Diels-Alder reactions of indole V. Reactions of 3-substituted indoles with heteroaromatic azadienes

1996; Elsevier BV; Volume: 37; Issue: 29 Linguagem: Inglês

10.1016/0040-4039(96)01017-9

ISSN

1873-3581

Autores

Scott C. Benson, Lily Lee, John K. Snyder,

Tópico(s)

Organic Chemistry Cycloaddition Reactions

Resumo

The inverse electron demand Diels-Alder reactions of 3-substituted indoles with 1,2,4-triazines and 1,2,4,5-tetrazines proceeded in excellent yields both inter- and intramolecularly. The cycloaddition of tryptophan with a tethered 1,2,4-triazine produced a diastereomerically pure cycloadduct.

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