Endogenous Metabolic Factor in Schizophrenic Behavior
1964; American Association for the Advancement of Science; Volume: 144; Issue: 3616 Linguagem: Inglês
10.1126/science.144.3616.311
ISSN1095-9203
AutoresH. H. Berlet, Christopher Bull, Harold E. Himwich, Herbert H. Kohl, Kunio Matsumoto, G.R. Pscheidt, J. Spaide, Thomas T. Tourlentes, José Manuel García Valverde,
Tópico(s)Metabolism and Genetic Disorders
ResumoExacerbations of schizophrenic behavior are associated with elevations of urinary tryptophan metabolites. Free tryptophan and methionine possibly arising from the breakdown of muscle protein may act like an endogenous metabolic factor which enhances behavioral worsening. Some of the apparently spontaneous activations of psychotic symptoms may be intensified by the endogenous liberation of these two compounds.
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