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Notes on the Pharmacology of Sodium Fluoroacetate—Compound 1080*†

1947; Elsevier BV; Volume: 36; Issue: 2 Linguagem: Inglês

10.1002/jps.3030360207

1930-2304

Justus C. Ward, Drew Spencer,

Poisoning and overdose treatments

Results of extensive lethal dose studies on rats, mice, ground squirrels, prairie dogs, cats, bobcats, dogs, coyotes, badgers, guinea pigs, sheep, cattle, horses, chickens, hawks, eagles, and other forms of life are presented. Descriptions of physiological reactions shown by the various species to the poison are given. Comparative toxicities of baits made with sodium fluoroacetate, thallium sulfate, white arsenic, zinc phosphide, and barium carbonate, as well as strychnine alkaloid, are shown. Secondary poisoning hazards to the predatory animals most susceptible to this poison are described. The utility of sodium fluoroacetate as an economic poison is discussed.