Antibiotic effectiveness: Balancing conservation against innovation
2014; American Association for the Advancement of Science; Volume: 345; Issue: 6202 Linguagem: Inglês
10.1126/science.1254163
ISSN1095-9203
Autores Tópico(s)Pharmaceutical and Antibiotic Environmental Impacts
ResumoAntibiotic effectiveness is a natural societal resource that is diminished by antibiotic use. As with other such assets, keeping it available requires both conservation and innovation. Conservation encompasses making the best use of current antibiotic effectiveness by reducing demand through vaccination, infection control, diagnostics, public education, incentives for clinicians to prescribe fewer antibiotics, and restrictions on access to newer, last-resort antibiotics. Innovation includes improving the efficacy of current drugs and replenishing effectiveness by developing new drugs. In this paper, I assess the relative benefits and costs of these two approaches to maintaining our ability to treat infections.
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