A Novel Biomimetic Hybrid Material Made of Silicified Collagen: Perspectives for Bone Replacement
2007; Wiley; Volume: 9; Issue: 12 Linguagem: Inglês
10.1002/adem.200700219
ISSN1527-2648
AutoresStefan H. Heinemann, Christiane Heinemann, Hermann Ehrlich, Michael Meyer, H. Baltzer, H. Worch, Thomas Hanke,
Tópico(s)Collagen: Extraction and Characterization
ResumoRecent findings have generated new interest in the biomaterial properties of silica-containing structures useful for bone replacement. The sol-gel-route seems to be most appropriate to mimic biological processing because it works under ambient conditions and furthermore allows the formation of a mineral phase from solution and the integration of a second component. The present work provides a strategy to mimic the natural processes of biosilicification under ambient conditions. By going beyond the nano- and micro-level, the authors established an advanced procedure for the preparation of monolithic silica-collagen hybrid xerogels.
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