Changes in TRH immunoreactivity in spinal cord after experimental spinal injury
1986; Elsevier BV; Volume: 7; Issue: 1 Linguagem: Inglês
10.1016/0143-4179(86)90073-9
ISSN1532-2785
AutoresAI Faden, Timothy G. Hill, Michael J. Kubek,
Tópico(s)Neuropeptides and Animal Physiology
ResumoConcentrations of immunoreactive TRH (TRH-ir) in rat spinal cord were examined after traumatic injury. TRH-ir was significantly increased at the injury site (thoracic region) and rostral areas (cervical region), and significantly decreased below the injury site. Changes were delayed and time-dependent. Since TRH may serve as an excitatory neurotransmitter within the spinal cord, these changes may contribute to the functional alterations observed after spinal injury.
Referência(s)