Backbone Rearrangement of 3β,4β-Epoxyfriedelane. A Formation of Germanicol and Solvent Effects
1977; Oxford University Press; Volume: 50; Issue: 12 Linguagem: Inglês
10.1246/bcsj.50.3381
ISSN1348-0634
AutoresMotoo Tori, Takahiko Tsuyuki, Takeyoshi Takahashi,
Tópico(s)Cancer Treatment and Pharmacology
ResumoAbstract In the reaction of 3β,4β-epoxyfriedelane with boron trifluoride etherate in benzene, a backbone rearragement proceeds up to D/E rings, giving germanicol as the main product, together with D:B-friedo-olean-5(10)-en-3β-ol, D:B-friedo-olean-5-en-3β-ol, and β-amyrin. The reaction product ratio of this reaction in various solvents was examined by HPLC.
Referência(s)