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The Effect of Allopurinol on Urinary Oxalate Excretion in Stone Formers

1978; Wiley; Volume: 50; Issue: 7 Linguagem: Inglês

10.1111/j.1464-410x.1978.tb06190.x

1365-2176

Rodney J. Scott, P.J.K. Paterson, Andrew Mathieson, Michael Smith,

Urinary Tract Infections Management

Allopurinol is a drug which could be valuable in the treatment of stone patients. In 29 subjects treated with 300 mg of the drug per day it has been found that there was a significant fall in urine oxalate excretion if the blood urate was above 330 mumol/l. In 10 subjects followed for 1 year the urine oxalate was significantly reduced and maintained at a lower level than the original.