Portal de Periódicos da CAPES

Identification of two new HLA‐B22 variants, HLA‐B*5509 and B*5606

2001; Wiley; Volume: 58; Issue: 1 Linguagem: Inglês

10.1034/j.1399-0039.2001.580108.x

1399-0039

Christina E.M. Voorter, Bouke G. Hepkema, Eva Mulkers, S P Lems, E.M. Van Den Berg‐Loonen,

Immunodeficiency and Autoimmune Disorders

In our recent study using high-resolution HLA-B locus typing by sequence-based typing (SBT) we identified 9 new alleles in a total of 355 unrelated individuals (4). Three of them concerned an allele belonging to the B22 group. One of them, B*5607, showed the unusual presence of a Bw4 sequence motif, as described previously (5). In this report the other two B22 variants are described; one belonging to the B55 specificity and named B*5509; the other one being a B*56 allele and assigned B*5606, which brings the total number of alleles belonging to the B22 group to 18.