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Risk estimation approach in Chagas disease is still needed

2010; Elsevier BV; Volume: 147; Issue: 2 Linguagem: Inglês

10.1016/j.ijcard.2010.12.044

1874-1754

Maria Carmo Pereira Nunes, Rodrigo Citton Padilha dos Reis, Enrico A. Colosimo, Antônio Luiz Pinho Ribeiro, Felipe Batista Lima Barbosa, José Luiz Padilha da Silva, Fernando Antônio Botoni, Márcia M. Barbosa, Manoel Otávio da Costa Rocha,

Cardiac Imaging and Diagnostics

Risk assessment of Chagas disease patients is essential for clinical decision making [ [1] Rassi Jr., A. Rassi A. Predicting prognosis in patients with Chagas disease: why are the results of various studies so different?. Int J Cardiol. 2010; 145: 64-65 Abstract Full Text Full Text PDF PubMed Scopus (9) Google Scholar ]. New markers of cardiovascular risk have recently been identified. However, whether these factors can contribute to overall risk prediction remains an important question [ [2] Hlatky M.A. Greenland P. Arnett D.K. et al. Criteria for evaluation of novel markers of cardiovascular risk: a scientific statement from the American Heart Association. Circulation. 2009; 119: 2408-2416 Crossref PubMed Scopus (930) Google Scholar ]. Although the conventionally used prognostic variable has been left ventricular ejection fraction, other parameters may allow more precise risk estimation. In particular, the ratio of early transmitral velocity to tissue Doppler mitral annular early diastolic velocity (E/e′) has become an accepted noninvasive method to estimate LV filling pressures for a variety of cardiac diseases [ [3] Nagueh S.F. Middleton K.J. Kopelen H.A. Zoghbi W.A. Quiñones M.A. Doppler tissue imaging: a noninvasive technique for evaluation of left ventricular relaxation and estimation of filling pressures. J Am Coll Cardiol. 1997; 30: 1527-1533 Abstract Full Text Full Text PDF PubMed Scopus (2567) Google Scholar ].