Revisão Revisado por pares

The dimensions of Creutzfeldt‐Jakob disease

1994; Wiley; Volume: 34; Issue: 10 Linguagem: Inglês

10.1046/j.1537-2995.1994.341095026981.x

ISSN

1537-2995

Autores

Laura Manuelidis,

Tópico(s)

Porphyrin Metabolism and Disorders

Resumo

TransfusionVolume 34, Issue 10 p. 915-928 The dimensions of Creutzfeldt-Jakob disease L. MANUELIDIS MD, Corresponding Author L. MANUELIDIS MD Professor and Head1Section of Neuropathology, P.O. Box 3333, Yale University School of Medicine, 310 Cedar Street, New Haven, CT 06510.Search for more papers by this author L. MANUELIDIS MD, Corresponding Author L. MANUELIDIS MD Professor and Head1Section of Neuropathology, P.O. Box 3333, Yale University School of Medicine, 310 Cedar Street, New Haven, CT 06510.Search for more papers by this author First published: October 1994 https://doi.org/10.1046/j.1537-2995.1994.341095026981.xCitations: 23Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 VandeWoude S, Richt JA, Zink MC, Rott R, Narayan O, Clements JE. A borna virus cDNA encoding a protein recognized by antibodies in humans with behavioral diseases. Science 1990; 250: 1278–81. 2 Yamaguchi K. Human T-lymphotropic virus type I in Japan. Lancet 1994; 343: 213–6. 3 White FA III, Ishaq M, Stoner GL, Frisque RJ. JC virus DNA is present in many human brain samples from patients without progressive multifocal leukoencephalopathy. J Virol 1992; 66: 5726–34. 4 Manuelidis L. Dementias, neurodegeneration, and viral mechanisms of disease from the perspective of human transmissible encephalopathies. Ann N Y Acad Sci 1994; 724: 259–81. 5 Jakob A. Die extrapyramidalen Erkrankungen mit besonderer Berucksichtigung der pathologischen Anatomie und Histologic und der Pathophysiologic de Bewegungsstorungen. In: OW Foerster, K Wilmanns, eds. Monographien aus dem Gesamtgebiete der Neurologie und Psychiatrie. Berlin: Springer 1923; 37: 215–345. 6 Manuelidis EE, Manuelidis L. Suggested links between different types of dementias: Creutzfeldt-Jakob disease, Alzheimer disease, and retroviral CNS infections. Alzheimer Dis Assoc Disord 1989; 3: 100–9. 7 Gibbs CJ, Gajdusek DC, Asher DM, et al. Creutzfeldt-Jakob disease (spongiform encephalopathy): transmission to the chimpanzee. Science 1968; 161: 388–9. 8 Gajdusek DC. Unconventional viruses and the origin and disappearance of kuru. Science 1977; 197: 943–60. 9 Manuelidis EE. Transmission of Creutzfeldt-Jakob disease from man to the guinea pig. Science 1975; 190: 571–2. 10 Manuelidis EE, Manuelidis L. Clinical and morphological aspects of transmissible Creutzfeldt-Jakob disease. Prog Neuropathol 1979; 4: 1–26. 11 Manuelidis L, Tesin DM, Sklaviadis T, Manuelidis EE. Astrocyte gene expression in Creutzfeldt-Jakob disease. Proc Natl Acad Sci U S A 1987; 84: 5937–41. 12 Manuelidis EE, de Figueiredo JM, Kim JH, Fritch WW, Manuelidis L. Transmission studies from blood of Alzheimer disease patients and healthy relatives. Proc Natl Acad Sci USA 1988; 85: 4898–901. 13 Manuelidis EE, Gorgacs EJ, Manuelidis L. Viremia in experimental Creutzfeldt-Jakob disease. Science 1978; 200: 1069–71. 14 Manuelidis EE, Kim JH, Mericangas JR, Manuelidis L. Transmission to animals of Creutzfeldt-Jakob disease from human blood. Lancet 1985; 2: 896–7. 15 Diringer H. Sustained viremia in experimental hamster scrapie. Arch Virol 1984; 82: 105–9. 16 Brown P, Preece MA, Will RG. Friendly fire in medicine: hormones, homografts, and Creutzfeldt-Jakob disease. Lancet 1992; 340: 24–7. 17 Dumble LJ, Klein RD. Creutzfeldt-Jakob legacy for Australian women treated with human pituitary gonadotropins (letter). Lancet 1992; 340: 847–8. 18 Manuelidis EE, Angelo JN, Gorgacz EJ, Kim JH, Manuelidis L. Experimental Creutzfeldt-Jakob disease transmitted via the eye with infected cornea. N Engl J Med 1977; 296: 1334–6. 19 Richard J, Thadani V, Kalb R, Manuelidis EE, Hadler J. Rapidly progressive dementia in a patient who received a cadaveric dura mater graft. MMWR Morb Mortal Wkly Rep 1987; 36: 49–55. 20 Collee JG. BSE: stocktaking 1993. Lancet 1993; 342: 790–3. 21 Gammie F. Weak evidence for human link to BSE infected meat. Nature 1994; 367: 402. 22 Manuelidis EE, Rorke LB. Transmission of Alpers' disease (chronic progressive encephalopathy) produces experimental Creutzfeldt-Jakob disease in hamsters. Neurology 1989; 39: 615–21. 23 Dimitrov D, Willey RL, Sato H, Chang U, Blumenthal R, Martin MA. Quantitation of human immunodeficiency virus type 1 infection kinetics. J Virol 1993; 67: 2182–90. 24 Diringer H, Ehlers B. Chemoprophy laxis of scrapie in mice. J Gen Virol 1991; 72: 457–60. 25 Manuelidis EE, Kim JH, Manuelidis L. Destructive white matter lesions in experimental Creutzfeldt-Jakob disease. In: LA Court, D Dormont, P Brown, DT Kingsbury, eds. Unconventional virus diseases of the central nervous system. Paris: Masson, 1986: 221–30. 26 Manuelidis L, Murdoch G, Manuelidis EE. Potential involvement of retroviral elements in human dementias. Ciba Found Symp 1988; 135: 117–34. 27 Bruce ME, McConnell I, Fraser H, Dickinson AG. The disease characteristics of different strains of scrapie in Sine congenic mouse lines: implications for the nature of the agent and host control of pathogenesis. J Gen Virol 1991; 72: 595–603. 28 Bruce ME, Dickinson AG. Biological evidence that scrapie has an independent genome. J Gen Virol 1987; 68: 79–89. 29 Weissmann C. A "unified theory" of prion propagation. Nature 1991; 352: 679–83. 30 Dickinson AG, Fraser H, McConnell I, Outram GW, Sales DI, Taylor DM. Extraneural competition between different scrapie agents leading to loss of infectivity. Nature 1975; 253: 556. 31 Kimberlin RH, Walker CA. Competition between strains of scrapie depends on the blocking agent being infectious. Intervirology 1985; 23: 74–81. 32 Eiden MV, Farrell K, Warsowe J, Mahan LC, Wilson CA. Characterization of a naturally occurring ecotropic receptor that does not facilitate entry of all ecotropic murine retroviruses. J Virol 1993; 67: 4056–61. 33 Prusiner SB. Novel proteinaceous infectious particles cause scrapie. Science 1982; 216: 136–44. 34 Merz PA, Somerville RA, Wisniewski HM, Manuelidis L, Manuelidis EE. Scrapie-associated fibrils in Creutzfeldt-Jakob disease. Nature 1983; 306: 474–6. 35 Diringer H, Gelderblom H, Hilmert H, Ozel M, Edelbluth C, Kimberlin RH. Scrapie infectivity, fibrils and low molecular weight protein. Nature 1983; 306: 476–8. 36 Manuelidis L, Valley S, Manuelidis EE. Specific proteins in Creutzfeldt-Jakob disease and scrapie share antigenic and carbohydrate determinants. Proc Natl Acad Sci U S A 1985; 82: 4263–7. 37 Manuelidis L, Sklaviadis T, Manuelidis EE. Evidence suggesting that PrP is not the infectious agent in Creutzfeldt-Jakob disease. EMBO J 1987; 6: 341–7. 38 Carr K. Creutzfeldt-Jakob verdict may prompt new claims. Nature 1993; 366: 98. 39 Manuelidis EE, Manuelidis L. A transmissible Creutzfeldt-Jakob disease-like agent is prevalent in the human population. Proc Natl Acad Sci U S A 1993; 90: 7724–8. 40 Eklund C, Hadlow NJ, Kennedy RC. Some properties of the scrapie agent and its behavior in mice. Proc Exp Biol 1963; 112: 974–9. 41 Alper T, Cramp WA, Haig DA, Clark MC. Does the agent of scrapie replicate without nucleic acid? Nature 1967; 214: 764–6. 42 Bell inger-Kawahara C, Cleaver JE, Diener TO, Prusiner SB. Purified scrapie prions resist inactivation by UV irradiation. J Virol 1987; 61: 159–66. 43 Griffith JS. Self-replication and scrapie. Nature 1967; 215: 1043–4. 44 Lax AJ, Millson GC, Manning EJ. Involvement of protein in scrapie agent infectivity. Res Vet Sci 1983; 34: 155–8. 45 Hope J, Morton LJ, Farquhar CF, Multhaup G, Beyreuther K, Kimberlin RH. The major polypeptide of scrapie-associated fibrils (SAF) has the same size, charge distribution and N-terminal protein sequence as predicted for the normal brain protein (PrP). EMBO J 1986; 5: 2591–7. 46 Czub M, Braig HR, Diringer H. Replication of the scrapie agent in hamsters infected intracerebrally confirms the pathogenesis of an amyloid-inducing virosis. J Gen Virol 1988; 69: 1753–6. 47 Allsop D, Ikeda S, Bruce M, Glenner GG. Cerebrovascular amyloid in scrapie-affected sheep reacts with antibodies to prion protein. Neurosci Lett 1988; 92: 234–9. 48 Rohwer RG. The scrapie agent: "a virus by any other name." CurrTop Microbiol Immunol 1991; 172: 195–232. 49 Xi YG, Ingrosso L, Ladogana A, Masullo C, Pocchiari M. Amphotericin B treatment dissociates in vivo replication of the scrapie agent from PrP accumulation. Nature 1992; 356: 598–601. 50 Sklaviadis T, Dreyer R, Manuelidis L. Analysis of Creutzfeldt-Jakob disease infectious fractions by gel permeation chromatography and sedimentation field flow fractionation. Virus Res 1992; 26: 241–54. 51 McBride PA, Eikelenbloom P, Kraal G, Fraser H, Bruce ME. PrP protein is associated with follicular dendritic cells of spleens and lymph nodes in uninfected and scrapie-infected mice. J Pathol 1992; 168: 413–8. 52 Miyamoto T, Sakaguchi S, Katamine S, Moriuchi R. The infectivity is dissociated from PrP accumulation in salivary gland of Creutzfeldt-Jakob disease agent-inoculated mice. Ann N Y Acad Sci 1994; 724: 310–3. 53 Sklaviadis TK, Manuelidis L, Manuelidis EE. Physical properties of the Creutzfeldt-Jakob disease agent. J Virol 1989; 63: 1212–22. 54 Prusiner SB. Molecular biology of prion diseases. Science 1991; 252: 1515–22. 55 Bueler H, Aguzzi A, Sailer A, et al. Mice devoid of PrP are resistant to scrapie. Cell 1993; 73: 1339–47. 56 Prusiner SB, Groth DF, Bolton DC, Kent SB, Hood LE. Purification and structural studies of a major scrapie prion protein. Cell 1984; 38: 127–34. 57 Manuelidis L, Sklaviadis T, Manuelidis EE. On the origin and significance of scrapie associated fibrils. In: LA Court, D Dormont, P Brown, DT Kinsbury, eds. Unconventional virus disease of the central nervous system. Paris: Masson, 1986; 489–507. 58 Brown P, Liberski PP. Wolff A, Gajdusek DC. Conservation of infectivity in purified fibrillary extracts of scrapie-infected hamster brain after sequential enzymatic digestion or poly-acrylamide gel electrophoresis. Proc Natl Acad Sci U S A 1990; 87: 7240–4. 59 Prusiner SB, Groth D, Serban A, Stahl N, Gabizon R. Attempts to restore scrapie prion infectivity after exposure to protein denaturants. Proc Natl Acad Sci U S A 1993; 90: 2793–7. 60 Chesebro B, Race R, Wehrly K, et al. Identification of scrapie prion protein-specific mRNA in scrapie-infected and uninfected brain. Nature 1985; 315: 331–3. 61 Raeber AJ, Borchelt DR. Scott M, Prusiner SB. Attempts to convert the cellular prion protein into the scrapie isoform in cell-free systems. J Virol 1992; 66: 6155–63. 62 Bolton DC, Bendheim PE. A modified host protein model of scrapie. Ciba Found Symp 1988; 135: 164–81. 63 Manuelidis L, Manuelidis EE. Recent developments in scrapie and Creutzfeldt-Jakob disease. Prog Med Virol 1985; 33: 78–98. 64 Forloni GF, Angeretti N, Chiesa R, et al. Neurotoxicity of a prion protein fragment. Nature 1993; 362: 543–6. 65 McKinley MP, Bolton DC, Prusiner SB. A protease-resistant protein is a structural component of the scrapie prion. Cell 1983; 35: 57–62. 66 Race R. The scrapie agent in vitro. Curr Top Microbiol Immunol 1991; 172: 181–93. 67 Aiken JM, Williamson JL, Borchardt LM, Marsh RF. Presence of mitochondrial D-loop DNA in scrapie-infected brain preparations enriched for prion protein. J Virol 1990; 64: 3265–8. 68 Rubenstein R, Merz PA, Kascsak R, et al. Scrapie-infected spleens: analysis of infectivity, scrapie-associated fibrils, and protease-resistant proteins. J Infect Dis 1991; 164: 29–35. 69 Race RE, Ernst D. Detection of proteinase K-resistant prion protein and infectivity in mouse spleen by 2 weeks after scrapie agent inoculation. J Gen Virol 1992; 73: 3319–23. 70 Prusiner SB, McKinley MP, Bowman KA, et al. Scrapie prions aggregate to form amyloid-like birefringent rods. Cell 1983; 35: 349–58. 71 Brion JP, Fraser H, Flament-Durand J, Dickinson AG. Amyloid scrapie plaques in mice, and Alzheimer senile plaques, share common antigens with tau, a microtubule-associated protein. Neurosci Lett 1987; 78: 113–8. 72 Oesch B, Teplow DB, Stahl N, Serban D, Hood LE, Prusiner SB. Identification of cellular proteins binding to the scrapie prion protein. Biochemistry 1990; 29: 5848–55. 73 Hunter N, Hope J, McConnell I, Dickinson AG. Linkage of the scrapie-associated fibril protein (PrP) gene and Sine using congenic mice and restriction fragment length polymorphism analysis. J Gen Virol 1987; 68: 2711–6. 74 Liao KJ, Lebo RV, Clawson GA, Smuckler EA. Human prion protein cDNA: molecular cloning, chromosomal mapping and biological implications. Science 1986; 233: 364–7. 75 Oesch B, Westaway D, Prusiner SB. Prion protein genes: evolutionary and functional aspects. Curr Topics Microbiol Immunol 1991; 172: 109–24. 76 Hsiao KK, Scott M, Foster D, Groth DF, DeArmond SJ, Prusiner SB. Spontaneous neurodegeneration in transgenic mice with mutant prion protein. Science 1990; 250: 1587–90. 77 Robertson M. Membrane proteins and minimalism. Nature 1991; 354: 183. 78 Hsiao KK. The genetics and transgenetics of human prion disease. Ann N Y Acad Sci 1994; 724: 241–5. 79 Kimberlin RH, Walker CA, Fraser H. The genomic identity of different strains of mouse scrapie is expressed in hamsters and preserved on reisolation in mice. J Gen Virol 1989; 70: 2017–25. 80 Bueler H, Fischer M, Lang Y, et al. Normal development and behavior of mice lacking the neuronal cell-surface PrP protein. Nature 1992; 356: 577–82. 81 Morrison LA, Fields BN, Dermody TS. Prolonged replication in the mouse central nervous system of reoviruses isolated from persistently infected cell cultures. J Virol 1993; 67: 3019–26. 82 Oldstone MB. Molecular anatomy of viral persistence. J Virol 1991; 65: 6381–6. 83 Baker HF, Ridley RM, Crow TJ. Experimental transmission of an autosomal dominant spongiform encephalopathy: does the infectious agent originate in the human genome? Br Med J (Clin Res Ed) 1985; 291: 299–302. 84 Manuelidis EE, Manuelidis L. Experiments on maternal transmission of Creutzfeldt-Jakob disease in guinea pigs. Proc Soc Exp Biol Med 1979; 160: 233–6. 85 Goldfarb LG, Mitrova E, Brown P, Toh BK, Gajdusek DC. Mutation in codon 200 of scrapie amyloid protein gene in two clusters of Creutzfeldt-Jakob disease in Slovakia. Lancet 1990; 336: 514–5. 86 Little BW, Brown PW, Rodgers-Johnson P, Perl DP, Gajdusek DC. Familial myoclonic dementia masquerading as Creutzfeldt-Jakob disease. Ann Neurol 1986; 20: 231–9. 87 Manetto VR, Medori R, Cortelli P, et al. Fatal familial insomnia: clinical and pathological study of five new cases. Neurology 1992; 42: 312–9. 88 Briese T, de la Torre JC, Lewis A, Ludwig H, Lipkin WI. Borna disease virus, a negative-strand RNA virus, transcribes in the nucleus of infected cells. Proc Natl Acad Sci U S A 1992; 89: 11486–9. 89 Gravel C, Kay DG, Jolicoeur P. Identification of the infected target cell type in spongiform myelopathy induced by the neurotropic Cas-Br-E murine leukemia virus. J Virol 1993; 67: 6648–58. 90 Levinson W, Rubin H. Radiation studies of avian tumor viruses and of Newcastle disease vims. Virology 1966; 28: 533–42. 91 R Weiss, N Teich, H Varmus, J Coffin, eds. RNA tumor viruses. 2nd ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1984. 92 Luo GX, Taylor J. Template switching by reverse transcriptase during DNA synthesis. J Virol 1990; 64: 4321–8. 93 Li Y, Ball LA. Nonhomologous RNA recombination during negative-strand synthesis of flock house virus RNA. J Virol 1993; 67: 3854–60. 94 Cascone PJ, Haydar TF, Simon AE. Sequences and structures required for recombination between virus associated RNAs. Science 1993; 260: 801–5. 95 Dickinson AG, Outram GW. Genetic aspects of unconventional virus infections: the basis of the virino hypothesis. Ciba Found Symp 1988; 135: 63–83. 96 Sklaviadis T, Manuelidis L, Manuelidis EE. Characterization of major peptides in Creutzfeldt-Jakob disease and scrapie. Proc Natl Acad Sci U S A 1986; 83: 6146–50. 97 Sklaviadis T, Akowitz A, Manuelidis EE, Manuelidis L. Nuclease treatment results in high specific purification of Creutzfeldt-Jakob disease infectivity with a density characteristic of nucleic acid-protein complexes. Arch Virol 1990; 112: 215–28. 98 Akowitz A, Sklaviadis T, Manuelidis EE, Manuelidis L. Nuclease-resistant polyadenylated RNAs of significant size are detected by PCR in highly purified Creutzfeldt-Jakob disease preparations. Microb Pathog 1990; 9: 33–45. 99 Meyer N, Rosenbaum V, Schmidt B, et al. Search for a putative scrapie genome in purified prion fractions reveals a paucity of nucleic acids. J Gen Virol 1991; 72: 37–49. 100 Oesch B, Groth DF, Prusiner SB, Weissmann C. Search for a scrapie-specific nucleic acid: a progress report. Ciba Found Symp 1988; 135: 209–23. 101 Kellings K, Meyer N, Mirenda C, Prusiner SB, Riesner D. Further analysis of nucleic acids in purified scrapie prion preparations by improved return refocusing gel electrophoresis. J Gen Virol 1992; 73: 1025–9. 102 Akowitz A, Sklaviadis T, Manuelidis L. Endogenous viral complexes with long RNA cosediment with the agent of Creutzfeldt-Jakob Disease. Nucleic Acids Res 1994; 22: 1101–7. 103 Manuelidis EE, Fritch WW, Kim JH, Manuelidis L. Immortality of cell cultures derived from brains of mice and hamsters infected with Creutzfeldt-Jakob disease agent. Proc Natl Acad Sci U S A 1987; 84: 871–5. 104 Oleszak EL, Murdoch G, Manuelidis L, Manuelidis EE. Growth factor production by Creutzfeldt Jakob disease cell lines. J Virol 1988; 62: 3103–8. 105 Contag CH, Harty JT, Plagemann PGW. Pathogenesis of age-dependent poliomyelitis of mice. In: RP Roos, ed. Molecular neurovirology. Totowa, NJ: Humana Press, 1992: 377–415. 106 Murdoch GH, Sklaviadis T, Manuelidis EE, Manuelidis L. Potential retroviral RNAs in Creutzfeldt-Jakob disease. J Virol 1990; 64: 1477–86. 107 Taruscio D, Manuelidis L. Integration site preferences of endogenous retroviruses. Chromosoma 1991; 101: 141–56. 108 Akowitz A, Manuelidis EE, Manuelidis L. Protected endogenous retroviral sequences copurify with infectivity in experimental Creutzfeldt-Jakob disease. Arch Virol 1993; 130: 301–16. 109 Sklaviadis T, Akowitz A, Manuelidis EE, Manuelidis L. Nucleic acid binding proteins in highly purified Creutzfeldt-Jakob disease preparations. Proc Natl Acad Sci U S A 1993; 90: 5713–7. 110 Heidmann O, Heidmann T. Retrotransposition of a mouse IAP sequence tagged with an indicator gene. Cell 1991; 64: 159–70. 111 Limjoco TI, Dickie P, Ikeda H, Silver J. Transgenic Fv-4 mice resistant to Friend virus. J Virol 1993; 67: 4163–8. 112 Caughey B, Ernst D, Race RE. Congo red inhibition of scrapie agent replication. J Virol 1993; 67: 6270–2. 113 Baba M, Nakajima M, Schols D, Pauwels R, Balzarini J, DeClercq E. Pentosanpolysulfate, a sulfated oligosaccharide, is a potent and selective anti-HIV agent in vitro. Antiviral Res 1988; 9: 335–43. 114 Ishihara M, Fedarko NS, Conrad HE. Involvement of phospatidylinositol and insulin in the coordinate regulation of proteoheparan sulfate metabolism and hepatocyte growth. J Biol Chem 1987; 262: 4708–16. Citing Literature Volume34, Issue10October 1994Pages 915-928 ReferencesRelatedInformation

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