Revisão Revisado por pares

Primary Carcinoid Tumors of the Kidney

2006; Lippincott Williams & Wilkins; Volume: 176; Issue: 6 Linguagem: Inglês

10.1016/j.juro.2006.07.129

ISSN

1527-3792

Autores

Frederico R. Romero, Soroush Rais–Bahrami, Sompol Permpongkosol, Samson W. Fine, Sahar Kohanim, Thomas W. Jarrett,

Tópico(s)

Pancreatic and Hepatic Oncology Research

Resumo

No AccessJournal of UrologyReview article1 Dec 2006Primary Carcinoid Tumors of the Kidney Frederico R. Romero, Soroush Rais-Bahrami, Sompol Permpongkosol, Samson W. Fine, Sahar Kohanim, and Thomas W. Jarrett Frederico R. RomeroFrederico R. Romero , Soroush Rais-BahramiSoroush Rais-Bahrami , Sompol PermpongkosolSompol Permpongkosol , Samson W. FineSamson W. Fine , Sahar KohanimSahar Kohanim , and Thomas W. JarrettThomas W. Jarrett View All Author Informationhttps://doi.org/10.1016/j.juro.2006.07.129AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We describe in detail the features of carcinoid tumors of the kidney. We evaluated possible prognostic factors. Materials and Methods: An extensive search was performed in the medical literature regarding primary carcinoid tumors of the kidney. Epidemiological, clinical, diagnostic, histopathological, therapeutic and prognostic data were evaluated. Several potential risk factors were compared with the incidence of metastases and clinical outcome of the patients. Results: A total of 56 case reports were reviewed. Median patient age was 49 years. Horseshoe kidneys were present in 17.8% of cases. Incidental diagnosis was made in 28.6% of patients. The most common symptom was abdominal or flank pain and neuroendocrine syndromes occurred with only 12.7% of primary renal carcinoid tumors. Of the patients 73.6% presented with tumors larger than 4 cm. Metastases were present in 45.6% of patients at initial diagnosis and almost 60% with tumors greater than 4 cm had metastases. Conclusions: Renal carcinoid is the second most prevalent genitourinary carcinoid in each sex, following testicular carcinoids in men and ovarian tumors in women. Significant adverse prognostic factors include age greater than 40 years, tumor size greater than 4 cm, purely solid tumors on the cut surface, mitotic rate higher than 1/10 high power fields, metastasis at initial diagnosis and tumors extending throughout the renal capsule. References 1 : Renal carcinoid producing the carcinoid syndrome. Med Times1966; 94: 895. Google Scholar 2 : Metastatic renal carcinoid: case report and review of the literature. Urology2003; 61: 838. Google Scholar 3 : Primary carcinoid tumor of kidney: Light and electron microscopy, and immunohistochemical study. Urology1988; 31: 517. Google Scholar 4 : Carcinoid in a horseshoe kidney: Morphology, immunohistochemistry, and cytogenetics. Cancer Genet Cytogenet1995; 84: 95. Google Scholar 5 : Horseshoe kidney is associated with an increased relative risk of primary renal carcinoid tumor. J Urol1997; 157: 2059. Link, Google Scholar 6 : A primary carcinoid tumor of the kidney: a case report and review of the literature. Abdom Imaging1996; 21: 464. Google Scholar 7 : Renal carcinoid and horseshoe kidney: a frequent association of two rare entities–a case report and review of the literature. J Surg Oncol1998; 68: 113. Google Scholar 8 : Primary carcinoid tumor in a horseshoe kidney. Int J Urol2000; 7: 184. Google Scholar 9 : Primary atypical carcinoid of the kidney: a classification is needed. Pathology2003; 35: 353. Google Scholar 10 : Carcinoid tumor originating in a horseshoe kidney. In Vivo2002; 16: 197. Google Scholar 11 : Carcinoid tumor occurring in a teratoid malformation of the kidney: An immunohistochemical study. Cancer1984; 54: 2305. Google Scholar 12 : Primary carcinoid tumour with ossification masquerading as calyx stone in a horseshoe kidney. Scand J Urol Nephrol1997; 31: 575. Google Scholar 13 : Carcinoid tumor occurring in cystic teratoma of the kidney: a case report. Cancer1976; 38: 1636. Google Scholar 14 : Primary carcinoid tumor arising in a mature teratoma of the kidney: a case report and review of the literature. Arch Pathol Lab Med2002; 126: 979. Google Scholar 15 : Primary carcinoid tumor in a mature teratoma of the kidney: ultrasonographic and computed tomographic findings. J Ultrasound Med2004; 23: 433. Google Scholar 16 : Primary carcinoid tumor arising in a retroperitoneal mature teratoma in an adult. Int J Urol2004; 11: 912. Google Scholar 17 : Rare case of carcinoid tumor arising within teratoma in kidney. Urology2005; 66: 658. Google Scholar 18 : Primary carcinoid tumor in a polycystic kidney. Pathol Int2003; 53: 317. Google Scholar 19 : Carcinoid tumor of the renal pelvis: report of a case with positive urine cytology. Diagn Cytopathol1995; 12: 360. Google Scholar 20 : Primary carcinoid of the renal pelvis. J Environ Pathol Toxicol Oncol1994; 13: 269. Google Scholar 21 : Primary renal carcinoid tumor. J Urol2004; 171: 338. Link, Google Scholar 22 : Endocrine tumour in kidney affecting small bowel structure, motility, and absorptive function. Gut1971; 12: 773. Google Scholar 23 : Primary renal carcinoid: computed tomography, ultrasound, and angiographic findings. J Comput Assist Tomogr1991; 15: 323. Google Scholar 24 : Case 3: Renal gastrinoma with Zollinger-Ellison syndrome. Pediatr Pathol1986; 6: 475. Google Scholar 25 : A renal vipoma. Br Med J1980; 281: 1323. Google Scholar 26 : Oncocytic carcinoid of the kidney associated with periodic Cushing's syndrome. Cancer1988; 61: 2136. Google Scholar 27 : Primary renal carcinoid tumor with molecular abnormality characteristic of conventional renal cell neoplasms. Diagn Mol Pathol1995; 4: 48. Google Scholar 28 : Primary renal carcinoid–case report. Australas Radiol1991; 35: 279. Google Scholar 29 : Carcinoid tumor of the kidney: The use of somatostatin receptor scintigraphy in diagnosis and management. Urol Oncol2000; 5: 108. Google Scholar 30 : Primary renal carcinoid tumor. Urology1993; 41: 295. Google Scholar 31 : Primary carcinoid of the kidney. Int Urol Nephrol1993; 25: 129. Google Scholar 32 : An analysis of 8305 cases of carcinoid tumors. Cancer1997; 79: 813. Google Scholar 33 : Carcinoids of the kidney: case report and literature review. Can J Surg1989; 32: 384. Google Scholar 34 : Carcinoid of the kidney: radiologic findings. AJR Am J Roentgenol1988; 150: 143. Google Scholar 35 : Carcinoid tumor of the kidney with morphologic and immunohistochemical profile of a hindgut endocrine tumor: report of a case. Ultrastruct Pathol1991; 15: 655. Google Scholar 36 : Primary renal carcinoid tumor. Scient World J2004; 4: 378. Google Scholar 37 : Primary renal carcinoid: report of a case. Cent Afr J Med1999; 45: 327. Google Scholar 38 : Primary carcinoid tumor of the kidney with special reference to its histogenesis. Pathol Int1996; 46: 894. Google Scholar 39 : Carcinoid tumor of the kidney presenting as a large abdominal mass: report of a case. Surg Today2004; 34: 86. Google Scholar 40 : Primary renal carcinoid tumor. Urology1988; 32: 564. Google Scholar 41 : Primary carcinoid of the kidney: Immunohistochemical and ultrastructural studies of five patients. Cancer1993; 72: 2660. Google Scholar 42 : Carcinoid tumor of kidney. Urology1979; 14: 610. Google Scholar 43 : Primary renal carcinoid: Case report and literature review. Arch Pathol Lab Med1993; 117: 855. Google Scholar 44 : Primary carcinoid of the kidney. Scand J Urol Nephrol1996; 30: 325. Google Scholar 45 : Primary renal carcinoid tumor with liver metastases detected with somatostatin receptor imaging. Urology2005; 65: 1002. Google Scholar 46 : Endocrine carcinoma of the kidney. Ultrastruct Pathol1997; 21: 307. Google Scholar 47 : Primary carcinoid tumor of the kidney: a light and electron microscopic, and immunohistochemical study. J Urol1983; 130: 333. Abstract, Google Scholar 48 : Carcinoidal renal tumor. J Urol1974; 111: 10. Link, Google Scholar 49 : Carcinoidal tumor of the kidney. Ultrastruct Pathol1983; 4: 51. Google Scholar 50 : Primary renal carcinoid natural history of the disease for ten years: case report. BMC Urol2002; 2: 1. Google Scholar James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland© 2006 by American Urological AssociationFiguresReferencesRelatedDetailsCited byCanacci A and MacLennan G (2018) Carcinoid Tumor of the KidneyJournal of Urology, VOL. 180, NO. 5, (2193-2193), Online publication date: 1-Nov-2008. Volume 176Issue 6December 2006Page: 2359-2366 Advertisement Copyright & Permissions© 2006 by American Urological AssociationKeywordskidneyriskcarcinoid tumorkidney neoplasmsneoplasm metastasisMetricsAuthor Information Frederico R. Romero More articles by this author Soroush Rais-Bahrami More articles by this author Sompol Permpongkosol More articles by this author Samson W. Fine More articles by this author Sahar Kohanim More articles by this author Thomas W. Jarrett More articles by this author Expand All Advertisement PDF downloadLoading ...

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