Portal de Periódicos da CAPES

A study of the natural history of acute leukemia with special reference to the duration of the disease and the occurrence of remissions

1951; Wiley; Volume: 4; Issue: 1 Linguagem: Inglês

10.1002/1097-0142(195101)4

1097-0142

Chester M. Southam, Lloyd F. Craver, Harold W. Dargeon, Joseph H. Burchenal,

Acute Myeloid Leukemia Research

CancerVolume 4, Issue 1 p. 39-59 ArticleFree Access A study of the natural history of acute leukemia with special reference to the duration of the disease and the occurrence of remissions Chester M. Southam M.D., Chester M. Southam M.D. Memorial Center for Cancer and Allied Diseases. New York, New York Damon Runyon Clinical Cancer Research Fellow.Search for more papers by this authorLloyd F. Craver M.D., Lloyd F. Craver M.D. Memorial Center for Cancer and Allied Diseases. New York, New YorkSearch for more papers by this authorHarold W. Dargeon M.D., Harold W. Dargeon M.D. Memorial Center for Cancer and Allied Diseases. New York, New YorkSearch for more papers by this authorJoseph H. Burchenal M.D., Joseph H. Burchenal M.D. Memorial Center for Cancer and Allied Diseases. New York, New YorkSearch for more papers by this author Chester M. Southam M.D., Chester M. Southam M.D. Memorial Center for Cancer and Allied Diseases. New York, New York Damon Runyon Clinical Cancer Research Fellow.Search for more papers by this authorLloyd F. Craver M.D., Lloyd F. Craver M.D. Memorial Center for Cancer and Allied Diseases. New York, New YorkSearch for more papers by this authorHarold W. Dargeon M.D., Harold W. Dargeon M.D. Memorial Center for Cancer and Allied Diseases. New York, New YorkSearch for more papers by this authorJoseph H. Burchenal M.D., Joseph H. Burchenal M.D. Memorial Center for Cancer and Allied Diseases. New York, New YorkSearch for more papers by this author First published: January 1951 https://doi.org/10.1002/1097-0142(195101)4:1 3.0.CO;2-GCitations: 88 AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 Aisner, M., and Hoxie, T. B.: Bone and joint pain in leukemia, simulating acute rheumatic fever and subacute bacterial endocarditis. New England J. Med. 238: 733–737, 1948. 10.1056/NEJM194805202382103 CASPubMedWeb of Science®Google Scholar 2 Benard, R., and Mallarme, J.: Un cas d'erythroleucémie aiguë remarquablement transformée par le sang de conserve. Sang 17: 186–191, 1946. Google Scholar 3 Bernard, J., and Bessis, M.: Réflexions sur le traitement des leucoses aiguës par l'exsanguino-transfusion. Sang 19: 45–50, 1948. CASPubMedGoogle Scholar 4 Bessis, M., and Bernard, J.: Remarquables résultats du traitement par l'exsanguino-transfusion d'un cas de leucémie aiguë. Bull. et mém. Soc. méd. d. hǒp. de Paris 63: 871–877, 1947. CASPubMedGoogle Scholar 5 Bessis, M., and Bernard, J.: A propos du traitement de la leucose aiguë par l'exsanguino-transfusion. Bull. et méin. Soc. méd d. hǒp. de Paris 64: 14–15, 1948. Google Scholar 6 Birge, R. F.; Jenks, A. L., Jr., and Davis, S. K.: Spontaneous remission in acute leukemia; report of a case complicated by eclampsia. J.A.M.A. 140: 589–592, 1949. 10.1001/jama.1949.02900420009003 CASPubMedWeb of Science®Google Scholar 7 Brandberg, O.: Studien über das klinische Bild der Leukosen und der sog. leukämoiden Reaktionen im Kindesalter. Acta paediat. (suppl. 1) 30: 1–286, 1943. Google Scholar 8 Burchenal, J. H.: The newer nitrogen mustards in the treatment of leukemia. Radiology 50: 494–499, 1948. 10.1148/50.4.494 CASPubMedWeb of Science®Google Scholar 9 Burchenal, J. H.; Myers, W. P. L.; Graver, L. F., and Karnofsky, D. A.: The nitrogen mustards in the treatment of leukemia. Cancer 2: 1–17, 1949. 10.1002/1097-0142(194901)2:1 3.0.CO;2-J CASPubMedWeb of Science®Google Scholar 10 Burchenal, J. H.; Karnofsky, D. A.; Southam, C. M.; Craver, L. F., Dargeon, H. W., and Rhoads, C. P.: The effects of 4-aminopteroylglutamic acid and related compounds on neoplastic diseas. Cancer 4: 1951. In press. PubMedGoogle Scholar 11 Cantieri, C.: Considerazioni sulla diagnosi clinica e sulle remissioni di certe forme di leucemia. I processi suppurativi come causa determinante di remissione. Minerva med. 1(Pt. sc.): 367, 1918. Google Scholar 12 Cooke, J. V.: Acute leukemia in children. J. A. M. A. 101: 432–435, 1933. 10.1001/jama.1933.02740310016004 Web of Science®Google Scholar 13 Cooke, J. V.: Experimental therapy of acute leucemia with extracts of bone marrow. J. Pediat. 13: 651–669, 1938. 10.1016/S0022-3476(38)80157-8 Web of Science®Google Scholar 14 Croizat, P.; Revol, L.; Viallet, and Morel, P.: Action remarquable des perfusions sanguines dans un cas de cryptoleucétuie aiguë. Normalisation passagère de la moelle et du sang. Sang 18: 474–480, 1947. CASPubMedGoogle Scholar 15 Dale, J. H., Jr.: Leucemia in childhood; a clinical and roentgenographic study of 72 cases. J. Pediat. 34: 421–432, 1949. 10.1016/S0022-3476(49)80256-3 PubMedWeb of Science®Google Scholar 16 Dameshek, W.: The use of folic acid antagonists in the treatment of acute and subacute leukemia. Blood 4: 168–171, 1949. CASPubMedWeb of Science®Google Scholar 17 Decourt, J.; Andre, R., and Guillemin, J.: Anémie grave fébrile avec aspect de leucose aiguë, traitée par la pénicilline associée à des transfusions répetées; guérison apparente depuis vingt mois. Presse med. 55: 378–379, 1947. Web of Science®Google Scholar 18 Diamond, H. D.; Craver, L. F.; Woodard, H. Q., and Parks, G. H.: Radioactive phosphorus. I. In the treatment of lymphatic leukemia. Cancer 3: 779–788, 1950. 10.1002/1097-0142(1950)3:5 3.0.CO;2-Y CASPubMedWeb of Science®Google Scholar 19 Doan, C. A.; Wiseman, B. K.; Wright, C-S.; Geyer, J. H.; Myers, W., and Myers, J. W.: Radioactive phosphorus. p32: a six-year clinical evaluation of internal radiation therapy. J. Lab. & Clin. Med. 32: 943–969, 1947. CASPubMedWeb of Science®Google Scholar 20 Dreyfus, B.: Les rémissions de la leucémie aiguë. Sang 19: 35–40, 1948. CASPubMedGoogle Scholar 21 Evans, T. C.; Lenz, M.; Donlan, C. P., and LeMay, M. J.: Effects of radioactive sodium on leukemia and allied diseases; preliminary report. Am. J. Roentgenol. 59: 469–481, 1948. CASPubMedWeb of Science®Google Scholar 22 Evensen, O. K., and Schartum-Hansen, H.: The symptomatology of aleukemic paramyeloblastic leukemia. Acta med. Scandinav. 107: 227–281, 1941. 10.1111/j.0954-6820.1941.tb11157.x Web of Science®Google Scholar 23 Falkenstein, D., and Fouler, W. M.: Acute lymphatic leukemia in childhood. Am. J. Dis. Child. 65: 445–454, 1943. Google Scholar 24 Farber, S.: Personal communication. Google Scholar 25 Farber, S.: Some observations on the effect of folic acid antagonists on acute leukemia and other forms of incurable cancer. Blood 4: 160–167, 1949. 10.1182/blood.V4.2.160.160 CASPubMedWeb of Science®Google Scholar 26 Farber, S.; Diamond, L. K.; Mercer, R. D.; Sylvester, R. F., Jr., and Wolff, J. A.: Temporary remissions in acute leukemia in children produced by folic acid antagonist, 4-aminopteroylglutamic acid (aminopterin). New England J. Med. 238: 787–793, 1948. 10.1056/NEJM194806032382301 CASPubMedWeb of Science®Google Scholar 27 Flinn, L. B.: Acute lymphatic leukemia in a child of 4 years with a severe granulopenic phase preceding a remission. Ann. Int. Med. 9: 458–469, 1935. 10.7326/0003-4819-9-4-458 Web of Science®Google Scholar 28 Forkner, C. E.: Leukemia and Allied Disorders. New York. Macmillan Co. 1938. 10.1097/00000441-193811000-00020 Google Scholar 29 Goodman, L., and Gilman, A.: The Pharmacological Basis of Therapeutics: A Textbook of Pharmacology, Toxicology and Therapeutics for Physicians and Medical Students. New York. Macmillan Co. 1941. Google Scholar 30 Jackson, H., Jr.: Acute leukemia with remissions. [Abstr.] Am. J. Cancer 26: 194–195, 1936. PubMedGoogle Scholar 31 Jackson, H., Jr.: The protean character of the leukemias and of the leukemoid states. New England J. Med. 220: 175–181, 1939. 10.1056/NEJM193902022200501 Web of Science®Google Scholar 32 Marcus, I. H.: Complete temporary recovery of long duration in acute aleucemic myeloid leucemia; case report. J. Lab. & Clin. Med. 21: 1006–1009, 1936. Web of Science®Google Scholar 33 May, E.; Cattan, R.; Frumusan, P., and Bilski-Pasqier, G.: Évolution d'une leucose aiguë traitée par les transfusions répétées et la pénicilline. Rev. d'hémat. 3: 13–28, 1948. Google Scholar 34 Miller, F. R., and Turner, D. L.: The action of specific stimulators on the hematopoietic system. Am. J. Med. Sc. 206: 146–158, 1943. 10.1097/00000441-194308000-00002 Google Scholar 35 Miller, F. R.; Herbut, P. A., and Jones, H. W.: The treatment of lymphoblastic leukemia with crude myelokentric acid. Blood 2: 15–39. 1947. PubMedWeb of Science®Google Scholar 36 Panton, P. N., and Valentine, F. C. O.: Chronic lymphoid leukaemia. Lancet 1: 914–916, 1929. 10.1016/S0140-6736(00)79186-0 Web of Science®Google Scholar 37 Parker, F.; Belding, and Daland, G. A.: The differentiation of histiocytic from monocytic leukemia. To be published. Google Scholar 38 Paroulek, J.: Septicémie agranulo-myéloblastique guérie par des transfusions sanguines répétées. Arch. d. mal. de coeur 20: 648–664, 1927. Google Scholar 39 Pearson, O. H.; Eliel, L. P.; Talbott, T. R., Jr.: Use of ACTH and cortisone in neoplastic diseases. Bull. New York Acad. Med. 26: 235–239, 1950. CASPubMedWeb of Science®Google Scholar 40 Pellegrini, G.: Casi di leucemia con remissione. Haematologica 28: 257–292, 1946. Google Scholar 41 Pierce, M.: Childhood leucemia. J. Pediat. 8: 66–95, 1936. 10.1016/S0022-3476(36)80214-5 Web of Science®Google Scholar 42 Piney, A.: Remissions in acute leukaemia: the role of blood transfusion in treatment. Acta haeat. 3: 1–16, 1950. Google Scholar 43 Pullen, D.: Lymphoblastic leukaemia treated with urethane. Brit. M. J. 1: 137–138, 1949. 10.1136/bmj.1.4594.137 CASPubMedWeb of Science®Google Scholar 44 Rappoport, A. E., and Kugel, V. H.: Monocytic leukemia; a case report illustrating variations in the clinical picture. Blood 2: 332–355, 1947. PubMedWeb of Science®Google Scholar 45 Reinhard, E. H.; Moore, C. V.; Bierbaum, O. S., and Moore, S.: Radioactive phosphorus as a therapeutic agent. Review of the literature and analysis of results of treatment of 155 patients with various blood dyscrasias, lymphomas, and other malignant neoplastic diseases. J. Lab. & Clin. Med. 31: 107–215, 1946. PubMedWeb of Science®Google Scholar 46 Riccitelli, L.: Coexistence ou succession de plusieurs hémopathies sur le měme sujet. (Considérations pathogéniques à propos d'un cas de myélose globale pseudo-aplastique à type pernicieux se terminant en lymphadénose subleucémique aiguë.) Sang 8: 237–268, 1934. Google Scholar 47 Riis, J.: Acute leukemia in children. Acta paediat. 33: 230–244, 1946. 10.1111/j.1651-2227.1946.tb16928.x Google Scholar 48 Rosenthal, N., and Harris, W.: Leukemia; its diagnosis and treatment. J. A. M. A. 104: 702–706, 1935. 10.1001/jama.1935.02760090006002 Web of Science®Google Scholar 49 Schenck, H. P., and Pepper, O. H. P.: Concerning the confusion between acute leukemia and infectious mononucleosis; with the report of a case of acute lymphoblastic leukemia with remission. Am. J. Med. Sc. 171: 320–331, 1926. 10.1097/00000441-192603010-00002 Web of Science®Google Scholar 50 Schiro, H. S., and Weiss, H. B.: Acute monocytic leukemia. Am. J. Med. 1: 307–312, 1946. 10.1016/0002-9343(46)90049-6 PubMedWeb of Science®Google Scholar 51 Schwind, J. L.: Partial maturation of leukemic myeloblasts following fresh plasma transfusions. Am. J. Med. Sc. 213: 170–175, 1947. 10.1097/00000441-194721320-00006 Web of Science®Google Scholar 52 Silverman, F. N.: The skeletal lesions in leukemia; clinical and roentgenographic observations in 103 infants and children, with a review of the literature. Am. J. Roentgenol. 59: 819–844, 1948. CASPubMedWeb of Science®Google Scholar 53 Smith, C. H.: Leucemia in childhood with onset simulating rheumatic disease. J. Pediat. 7: 390–400, 1935. 10.1016/S0022-3476(35)80215-1 Web of Science®Google Scholar 54 Southam, C. M.; Craver, L. F., and Kenney, F.: Long remission in a case of apparent eosinophilic leukemia treated with radioactive phosphorus. To be published. Google Scholar 55 Southam, C. M.; Goldsmith, Y., and Burchenal, J.: Heterophile antibodies and antigens in neoplastic diseases. Cancer 4: 1951 In press. 10.1002/1097-0142(195109)4:5 3.0.CO;2-A PubMedWeb of Science®Google Scholar 56 Thiersch, J. B.: Bone-marrow changes in man after treatment with aminopterin, amethopterin, and aminoanfol; with special reference to megaloblastosis and tumor remission. Cancer 2: 877–883, 1949. 10.1002/1097-0142(194909)2:5 3.0.CO;2-0 CASPubMedWeb of Science®Google Scholar 57 Turner, K.: Personal communication. Google Scholar 58 Ward, G.: The infective theory of acute leukemia. Brit. J. Child. Dis. 14: 10–20, 1917. Google Scholar 59 Warren, S. L.: Acute leukemia; a review of the literature and of 28 new cases. Am. J. Med. Sc. 178: 490–500, 1929. 10.1097/00000441-192910000-00003 Web of Science®Google Scholar 60 Whitby, L. E. H., and Christie, J. M.: Monocytic leukemia. Lancet 1: 80–82, 1935. 10.1016/S0140-6736(01)29149-1 Web of Science®Google Scholar 61 Wolman, I. J.; Eglick, P.; Dickstein, B., and Githens, J.: Leukemia in childhood; preliminary report of response to aminopterin. Pennsylvania M. J. 52: 474–481, 1948–49. PubMedGoogle Scholar Citing Literature Volume4, Issue1January 1951Pages 39-59 ReferencesRelatedInformation