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Plasma immunoreactive beta-endorphin response to glucose ingestion in human obesity

1984; Elsevier BV; Volume: 5; Issue: 4 Linguagem: Inglês

10.1016/s0195-6663(84)80005-7

1095-8304

Carl J. Getto, Donald T. Fullerton, Ian H. Carlson,

Pain Mechanisms and Treatments

Following the oral administration of 100 g of glucose, morbidly-obese subjects and non-obese controls demonstrated increased levels of plasma immunoreactive beta-endorphin. There was a slow rise in plasma immunoreactive beta-endorphin in the non-obese controls throughout the 3-h observation period. The obese subjects demonstrated a delayed and significantly greater rise of plasma immunoreactive beta-endorphin, when compared to the controls. These findings may have implications for further research in human obesity.