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Ethynylbenzenoid metabolites of Antrodia camphorata : synthesis and inhibition of TNF expression

2013; Royal Society of Chemistry; Volume: 12; Issue: 7 Linguagem: Inglês

10.1039/c3ob42333f

1477-0539

Marco R. Buccini, Kathryn A. Punch, Belinda J. Kaskow, Gavin R. Flematti, Brian W. Skelton, Lawrence J. Abraham, Matthew Piggott,

Biological and pharmacological studies of plants

Antrocamphin A and B, and (±)- epi -antrodioxolanone have been synthesised from a common precursor. Antrocamphin A displays anti-inflammatory activity but is also cytotoxic.