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Cutaneous Manifestations of Chronic Graft-versus-Host Disease

2006; Elsevier BV; Volume: 12; Issue: 11 Linguagem: Inglês

10.1016/j.bbmt.2006.08.043

1523-6536

Sharon R. Hymes, Maria L. Turner, Richard E. Champlin, Daniel R. Couriel,

Skin and Cellular Biology Research

Cutaneous chronic graft versus host disease has traditionally been classified into lichenoid and scleroderma-like forms. However, the initial presentation is sometimes subtle and a variety of less common cutaneous manifestation may be prevalent. This clinical review focuses on the lesional morphology of chronic graft versus host disease, and presents a classification system that may prove useful in early diagnosis. In addition, this approach may help to facilitate the correlation of different morphologic entities with outcome and response to therapy.