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Dapsone-Induced Hypersensitivity Pneumonitis Mimicking Pneumocystis carinii Pneumonia in a Patient with AIDS

2004; Elsevier BV; Volume: 327; Issue: 3 Linguagem: Inglês

10.1097/00000441-200403000-00010

1538-2990

Melissa Tobin‐D’Angelo, Susan M. Ray, Mark D. King, Maarouf Hoteit, Katia V. Brown,

Drug-Induced Adverse Reactions

Interstitial pneumonitis, often related to infectious etiologies, occurs commonly in HIV-infected patients. However, hypersensitivity pneumonitis from noninfectious etiologies, including environmental stimuli or drug exposure, is an unusual etiology of interstitial pneumonitis in HIV-infected patients. We report a patient with AIDS who developed a dapsone-induced hypersensitivity pneumonitis mimicking Pneumocystis carinii (PCP) pneumonia. We believe drug-induced hypersensitivity pneumonitis should be considered in the differential diagnosis of interstitial pneumonia in HIV-infected patients in whom infectious etiologies have been ruled out.