Portal de Periódicos da CAPES

Mechanics of ventricular diastole

1970; Oxford University Press; Volume: 4; Issue: 4 Linguagem: Inglês

10.1093/cvr/4.4.423

1755-3245

John V. Tyberg, Wilbert J. Keon, Edmund H. Sonnenblick, Charles W. Urschel,

Mechanical Circulatory Support Devices

An isolated canine heart preparation was developed which permitted evaluation of the time course of pressure and flow during ventricular diastole. Negative diastolic ventricular pressures were observed after inflow occluded ejections from a wide range of end diastolic volumes. The results are evaluated in the context of recent observations on myocardial ultrastructure and geometry and potential clinical implications are discussed.