The Reduction of Infarct Size — An Idea Whose Time (For Testing) Has Come
1974; Lippincott Williams & Wilkins; Volume: 50; Issue: 2 Linguagem: Inglês
10.1161/01.cir.50.2.206
ISSN1524-4539
AutoresEugene Braunwald, Peter R. Maroko,
Tópico(s)Cardiac Arrest and Resuscitation
ResumoHomeCirculationVol. 50, No. 2The Reduction of Infarct Size — An Idea Whose Time (For Testing) Has Come Free AccessResearch ArticlePDF/EPUBAboutView PDFSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toFree AccessResearch ArticlePDF/EPUBThe Reduction of Infarct Size — An Idea Whose Time (For Testing) Has Come EUGENE BRAUNWALD and PETER R. MAROKO EUGENE BRAUNWALDEUGENE BRAUNWALD From the Departments of Medicine, Harvard Medical School and the Peter Bent Brigham Hospital, Boston, Massachusetts. and PETER R. MAROKOPETER R. MAROKO From the Departments of Medicine, Harvard Medical School and the Peter Bent Brigham Hospital, Boston, Massachusetts. Originally published1 Aug 1974https://doi.org/10.1161/01.CIR.50.2.206Circulation. 1974;50:206–209 Previous Back to top Next FiguresReferencesRelatedDetailsCited By Joner M and Lahmann A (2020) Cardioprotection for Reduction of Infarct Size — Ancient Dogma for Some Time to Come, Cardiovascular Revascularization Medicine, 10.1016/j.carrev.2020.09.010, 21:12, (1585-1586), Online publication date: 1-Dec-2020. Heusch G (2019) Myocardial ischemia: lack of coronary blood flow, myocardial oxygen supply-demand imbalance, or what?, American Journal of Physiology-Heart and Circulatory Physiology, 10.1152/ajpheart.00139.2019, 316:6, (H1439-H1446), Online publication date: 1-Jun-2019. Buja L, Barth R, Krueger G, Brodsky S and Hunter R (2019) The Importance of the Autopsy in Medicine: Perspectives of Pathology Colleagues, Academic Pathology, 10.1177/2374289519834041, 6, (2374289519834041), Online publication date: 1-Jan-2019. Heusch G (2016) Myocardial Ischemia, Circulation Research, 119:2, (194-196), Online publication date: 8-Jul-2016. Buja L and Vander Heide R (2016) Pathobiology of Ischemic Heart Disease: Past, Present and Future, Cardiovascular Pathology, 10.1016/j.carpath.2016.01.007, 25:3, (214-220), Online publication date: 1-May-2016. Batchu S, Chaudhary K, Zlobine I, Pawa J and Seubert J (2016) Fatty Acids and Cardiac Ischemia Reperfusion Injury Handbook of Lipids in Human Function, 10.1016/B978-1-63067-036-8.00003-2, (39-83), . Rentrop K and Feit F (2015) Reperfusion therapy for acute myocardial infarction: Concepts and controversies from inception to acceptance, American Heart Journal, 10.1016/j.ahj.2015.08.005, 170:5, (971-980), Online publication date: 1-Nov-2015. Thompson P (2013) Acute Coronary Syndromes: Much Progress, New Challenges, Clinical Therapeutics, 10.1016/j.clinthera.2013.07.333, 35:8, (1054-1057), Online publication date: 1-Aug-2013. Eapen Z, Tang W, Felker G, Hernandez A, Mahaffey K, Lincoff A and Roe M (2012) Defining Heart Failure End Points in ST-Segment Elevation Myocardial Infarction Trials, Circulation: Cardiovascular Quality and Outcomes, 5:4, (594-600), Online publication date: 1-Jul-2012. Selvester R, Strauss D and Wagner G (2012) Myocardial Infarction Electrocardiology, 10.1007/978-0-85729-874-4_4, (169-264), . Jolicoeur E and Granger C (2011) Inflammation and Immunity as Targets for Drug Therapy in Acute Coronary Syndrome Acute Coronary Syndromes: A Companion to Braunwald's Heart Disease, 10.1016/B978-1-4160-4927-2.00025-6, (271-288), . Sloman J and Julian D (2011) History of the coronary (cardiac) care unit Coronary Care Manual, 10.1016/B978-0-7295-3927-2.10001-6, (2-3), . (2010) , Japanese Journal of Electrocardiology, 10.5105/jse.30.312, 30:4, (312-326), . Selvester R, Strauss D and Wagner G (2010) Myocardial Infarction Comprehensive Electrocardiology, 10.1007/978-1-84882-046-3_16, (651-746), . Parham W, Edelstein K, Unger B and Mooney M (2009) Therapeutic hypothermia for acute myocardial infarction: Past, present, and future, Critical Care Medicine, 10.1097/CCM.0b013e3181ab311d, 37:Supplement, (S234-S237), Online publication date: 1-Jul-2009. Wang Z, Li M, Wu W, Tan H and Geng D (2008) Ginsenoside Rb1 Preconditioning Protects Against Myocardial Infarction After Regional Ischemia and Reperfusion by Activation of Phosphatidylinositol-3-kinase Signal Transduction, Cardiovascular Drugs and Therapy, 10.1007/s10557-008-6129-4, 22:6, (443-452), Online publication date: 1-Dec-2008. Maximilian Buja L and Vela D (2008) Cardiomyocyte death and renewal in the normal and diseased heart, Cardiovascular Pathology, 10.1016/j.carpath.2008.02.004, 17:6, (349-374), Online publication date: 1-Nov-2008. Granger C and Patel M (2007) The Search for Myocardial Protection, Journal of the American College of Cardiology, 10.1016/j.jacc.2007.02.074, 50:5, (406-408), Online publication date: 1-Jul-2007. Pfeffer M (2007) Myocardial Infarction: Risks and Hope Cardiovascular Regeneration and Stem Cell Therapy, 10.1002/9780470988909.ch22, (211-217) Taqueti V, Mitchell R and Lichtman A (2006) PROTECTING THE PUMP: Controlling Myocardial Inflammatory Responses, Annual Review of Physiology, 10.1146/annurev.physiol.68.040104.124611, 68:1, (67-95), Online publication date: 1-Jan-2006. Nikus K, Eskola M, Niemelä K and Sclarovsky S (2005) Modern morphologic electrocardiographic interpretation—a valuable tool for rapid clinical decision making in acute ischemic coronary syndromes, Journal of Electrocardiology, 10.1016/j.jelectrocard.2004.09.016, 38:1, (4-6), Online publication date: 1-Jan-2005. de Zwaan C, van Dieijen-Visser M and Hermens W (2003) Prevention of Cardiac Cell Injury During Acute Myocardial Infarction, American Journal of Cardiovascular Drugs, 10.2165/00129784-200303040-00003, 3:4, (245-251), . Christenson R and Azzazy H (2003) Assessing Reperfusion and Prognostic Infarct Sizing with Biochemical Markers Cardiac Markers, 10.1007/978-1-59259-385-9_4, (59-86), . Roe M, Ohman E, Maas A, Christenson R, Mahaffey K, Granger C, Harrington R, Califf R and Krucoff M (2001) Shifting the open-artery hypothesis downstream: the quest for optimal reperfusion, Journal of the American College of Cardiology, 10.1016/S0735-1097(00)01101-3, 37:1, (9-18), Online publication date: 1-Jan-2001. Roe M (2000) Treatment strategies for microvascular dysfunction following acute myocardial infarction, Current Cardiology Reports, 10.1007/s11886-000-0053-y, 2:5, (405-410), Online publication date: 1-Sep-2000. Murry C, Zhang M and Reinecke H (2000) Myocardial infarction, infarct repair, and strategies for muscle regeneration Molecular Approaches to Heart Failure Therapy, 10.1007/978-3-642-57710-9_20, (298-315), . Mazur W, Bitar J, Lechin M, Grinstead W, Khalil A, Khan M, Sekili S, Zoghbi W, Raizner A and Kleiman N (1998) Coronary flow reserve may predict myocardial recovery after myocardial infarction in patients with TIMI grade 3 flow, American Heart Journal, 10.1053/hj.1998.v136.89905, 136:2, (335-344), Online publication date: 1-Aug-1998. Taber L and Podszus W (1997) A laminated shell model for the infarcted left ventricle, International Journal of Solids and Structures, 10.1016/0020-7683(95)00295-2, 34:2, (223-241), Online publication date: 1-Jan-1997. Ross J (1994) Eugene braunwald, Clinical Cardiology, 10.1002/clc.4960170310, 17:3, (160-162), Online publication date: 1-Mar-1994. Hibbard M, Holmes D, Bailey K, Reeder G, Bresnahan J and Gersh B (1992) Percutaneous transluminal coronary angioplasty in patients with cardiogenic shock, Journal of the American College of Cardiology, 10.1016/S0735-1097(10)80285-2, 19:3, (639-646), Online publication date: 1-Mar-1992. Cicutti N, Rakusan K and Downey H (1992) Colored microspheres reveal interarterial microvascular anastomoses in canine myocardium, Basic Research in Cardiology, 10.1007/BF00796525, 87:4, (400-409), . Alpert J (1991) Importance of the pharmacological profile of thrombolytic agents in clinical practice, The American Journal of Cardiology, 10.1016/0002-9149(91)90298-Y, 68:16, (3-7), Online publication date: 1-Dec-1991. Woo K (1990) Conduction defects in acute myocardial infarction in the Chinese in Hong Kong, International Journal of Cardiology, 10.1016/0167-5273(90)90090-R, 26:3, (325-334), Online publication date: 1-Mar-1990. Mullane K and Smith C (1990) The role of leukocytes in ischemic damage, reperfusion injury and repair of the myocardium Pathophysiology of Severe Ischemic Myocardial Injury, 10.1007/978-94-009-0475-0_12, (239-267), . Selzer A (1989) Does thrombolytic therapy reduce infarct size?, Journal of the American College of Cardiology, 10.1016/0735-1097(89)90324-0, 13:6, (1431-1434), Online publication date: 1-May-1989. Lee L, Bates E, Pitt B, Walton J, Laufer N and O'Neill W (1988) Percutaneous transluminal coronary angioplasty improves survival in acute myocardial infarction complicated by cardiogenic shock., Circulation, 78:6, (1345-1351), Online publication date: 1-Dec-1988. Zannad F, Amor M, Karcher G, Maurin P, Ethevenot G, Sebag C, Bertrand A, Pernot C and Gilgenkrantz J (1988) Effect of diltiazem on myocardial infarct size estimated by enzyme release, serial thallium-201 single-photon emission computed tomography and radionuclide angiography, The American Journal of Cardiology, 10.1016/0002-9149(88)91149-6, 61:15, (1172-1177), Online publication date: 1-Jun-1988. Hearse D (1988) The protection of the ischemic myocardium: Surgical success v clinical failure?, Progress in Cardiovascular Diseases, 10.1016/0033-0620(88)90004-7, 30:6, (381-402), Online publication date: 1-May-1988. Betriu A, Heras M and Sanz G (1988) Thrombolysis in Acute Myocardial Infarction Therapeutics in Cardiology, 10.1007/978-94-009-1333-2_70, (630-638), . Godin D and Bhimji S (1987) Effects of allopurinol on myocardial ischemic injury induced by coronary artery ligation and reperfusion, Biochemical Pharmacology, 10.1016/0006-2952(87)90137-7, 36:13, (2101-2107), Online publication date: 1-Jul-1987. Müller B, Maaß B, Stürzebecher C and Witt W (1987) Effects of Iloprost on Arrhythmias and Infarct Size in Rats After Coronary Artery Ligation Prostacyclin and Its Stable Analogue Iloprost, 10.1007/978-3-642-71499-3_21, (195-204), . Mueller B, Maass B, Krause W and Witt W (1986) Limitation of myocardial unperfused area and necrotic zone 24 hours and 7 days after coronary artery ligation in rats by the stable prostacyclin analogue iloprost, Prostaglandins, Leukotrienes and Medicine, 10.1016/0262-1746(86)90054-5, 21:3, (331-340), Online publication date: 1-Mar-1986. Mushlin P, Boucek R, Parrish M, Graham T and Olson R (1985) Beneficial effects of perfluorochemical artificial blood on cardiac function following coronary occlusion, Life Sciences, 10.1016/0024-3205(85)90305-4, 36:22, (2093-2102), Online publication date: 1-Jun-1985. Kubler W and Doorey A (1985) Reduction of infarct size. An attractive concept: useful--or possible--in humans?, Heart, 10.1136/hrt.53.1.5, 53:1, (5-8), Online publication date: 1-Jan-1985. Isner J and Roberts W (1985) Pathologic Anatomy of Acquired Ventricular Disease The Ventricle, 10.1007/978-1-4613-2599-4_1, (1-40), . Chatterjee K and Parmley W (1985) Therapy of Acute Myocardial Infarction Diagnosis and Therapy of Coronary Artery Disease, 10.1007/978-1-4613-2569-7_13, (357-402), . Peck W, Mancini G, Slutsky R, Mattrey R and Higgins C (1984) In vivo assessment by computed tomography of the natural progression of infarct size, left ventricular muscle mass and function after acute myocardial infarction in the dog, The American Journal of Cardiology, 10.1016/0002-9149(84)90527-7, 53:7, (929-935), Online publication date: 1-Mar-1984. Weintraub W, Hattori S, Akizuki S, Agarwal J, Bodenheimer M, Banka V and Helfant R (1984) Influence of nifedipine on collateral blood flow during acute ischemia in the dog, Journal of the American College of Cardiology, 10.1016/S0735-1097(84)80017-0, 3:2, (334-340), Online publication date: 1-Feb-1984. Slutsky R, Peck W, Mancini G, Mattrey R and Higgins C (1984) Myocardial infarct size determined by computed transmission tomography in canine infarcts of various ages and in the presence of coronary reperfusion, Journal of the American College of Cardiology, 10.1016/S0735-1097(84)80440-4, 3:1, (138-142), Online publication date: 1-Jan-1984. Mancini G, Peck W, Slutksy R, Ross J and Higgins C (1984) Use of computerized tomography to assess myocardial infarct size and ventricular function in dogs during acute coronary occlusion and reperfusion, The American Journal of Cardiology, 10.1016/0002-9149(84)90440-5, 53:2, (282-289), Online publication date: 1-Jan-1984. Silke B, Verma S, Nelson G and Taylor S (1984) Effects of Alpha-Beta Blockade on Cardiac Performance in Hypertension Complicating Myocardial Infarction Balanced Alpha/Beta Blockade of Adrenoceptors / Balancierte Blockade von Alpha- und Beta-Adrenozeptoren, 10.1007/978-3-663-20205-9_21, (197-205), . Goslinga H (1984) Specific Measuring Methods Blood Viscosity and Shock, 10.1007/978-3-642-69260-4_8, (77-90), . Catinella F, Cunningham J, Glassman E, Laschinger J, Baumann F and Spencer F (1983) Left atrium-to-femoral artery bypass: Effectiveness in reduction of acute experimental myocardial infarction, The Journal of Thoracic and Cardiovascular Surgery, 10.1016/S0022-5223(19)39065-8, 86:6, (887-896), Online publication date: 1-Dec-1983. Nowakowski J (1983) Acute Alveolar Edema, Emergency Medicine Clinics of North America, 10.1016/S0733-8627(20)30792-6, 1:2, (313-343), Online publication date: 1-Aug-1983. Dole W and O'Rourke R (1983) Pathophysiology and management of cardiogenic shock, Current Problems in Cardiology, 10.1016/0146-2806(83)90033-6, 8:3, (1-72), Online publication date: 1-Jun-1983. Slutsky R, Mattrey R, Long S and Higgins C (1983) In vivo estimation of myocardial infarct size and left ventricular function by prospectively gated computerized transmission tomography., Circulation, 67:4, (759-765), Online publication date: 1-Apr-1983. Patterson R, Horowitz S, Eng C, Meller J, Goldsmith S, Pichard A, Halgash D, Herman M and Gorlin R (1983) Can noninvasive exercise test criteria identify patients with left main or 3-vessel coronary disease after a first myocardial infarction?, The American Journal of Cardiology, 10.1016/S0002-9149(83)80066-6, 51:3, (361-372), Online publication date: 1-Feb-1983. von Essen R, Merx W, Effert S, Hinsen R, Silny J and Rau G (1983) Abilities and Limitations of Precordial Mapping in Acute Myocardial Infarction Advances in Noninvasive Cardiology, 10.1007/978-94-009-6720-5_18, (167-172), . Buchweitz E, Bottalico J and Weiss H (1982) Effect of ouabain on O2 supply/demand in normal and ischemic heart, Basic Research in Cardiology, 10.1007/BF01907946, 77:5, (552-561), Online publication date: 1-Sep-1982. Alivizatos P, Guerraty A and Lower R (1982) Circulatory Assistance with a Cardiac Allograft after Exclusion of the Canine Left Ventricle, The Annals of Thoracic Surgery, 10.1016/S0003-4975(10)60873-9, 34:2, (132-137), Online publication date: 1-Aug-1982. Patterson R, Weintraub W, Halgash D, Miao J, Rogers J and Kupersmith J (1982) Spatial distribution of [14C]-lidocaine and blood flow in transmural and lateral border zones of ischemic canine myocardium, The American Journal of Cardiology, 10.1016/0002-9149(82)90010-8, 50:1, (63-73), Online publication date: 1-Jul-1982. Horowitz R and Morganroth J (1982) Immediate detection of early high-risk patients with acute myocardial infarction using two-dimensional echocardiographic evaluation of left ventricular regional wall motion abnormalities, American Heart Journal, 10.1016/0002-8703(82)90393-3, 103:5, (814-822), Online publication date: 1-May-1982. Cairns J, Holder D, Tanser P and Missirlis E (1982) Intravenous hyaluronidase therapy for myocardial infarction in man: double-blind trial to assess infarct size limitation., Circulation, 65:4, (764-771), Online publication date: 1-Apr-1982. Hjalmarson Å (1982) BETA BLOCKING AGENTS: CURRENT STATUS IN THE PREVENTION OF SUDDEN CORONARY DEATH, Annals of the New York Academy of Sciences, 10.1111/j.1749-6632.1982.tb55226.x, 382:1 Sudden Corona, (305-323), Online publication date: 1-Mar-1982. Hellstrom H (1982) The injury-spasm (ischemia-induced hemostatic vasoconstrictive) and vascular autoregulatory hypothesis of ischemic disease, The American Journal of Cardiology, 10.1016/0002-9149(82)91962-2, 49:4, (802-810), Online publication date: 1-Mar-1982. Timmis A, Fowler M, Jaggarao N, Vincent R and Chamberlain D (2012) Role of labetalol in acute myocardial infarction., British Journal of Clinical Pharmacology, 10.1111/j.1365-2125.1982.tb01898.x, 13:S1, (111S-114S), Online publication date: 1-Feb-1982. Nieminen M and Heikkilä J (2009) Usefulness of Multiaxis Echocardiography in Assessment of the Left Ventricle in Ischemic Heart Disease, Acta Medica Scandinavica, 10.1111/j.0954-6820.1982.tb08539.x, 212:S668, (161-197) Roskamm H, Weisswange A, Langosch W, Hahn G, Reindell A, Kalusche D, Bubenheimer P, Ritter B, Samek L and Schmuziger H (1982) Coronarerkrankungen Herzkrankheiten, 10.1007/978-3-642-96617-0_40, (907-1054), . Bailey J (1981) Electrophysiological effects of hypertonic sucrose solutions on canine cardiac Purkinje fibers., Circulation Research, 49:5, (1112-1118), Online publication date: 1-Nov-1981. Ostrogorskii Y, Afonskaya N, Cherpachenko N, Rozonov Y, Kaverina N and Ruda M (1981) Effect of nitroglycerin on size of an experimental myocardial infarct, Bulletin of Experimental Biology and Medicine, 10.1007/BF00829786, 92:2, (1067-1069), Online publication date: 1-Aug-1981. Ramanathan K, Bodenheimer M, Banka V and Helfant R (1981) Natural history of contractile abnormalities after acute myocardial infarction in man: severity and response to nitroglycerin as a function of time., Circulation, 63:4, (731-738), Online publication date: 1-Apr-1981. Glogar D, Kloner R, Muller J, DeBoer L, Braunwald E and Clark L (1981) Fluorocarbons Reduce Myocardial Ischemic Damage After Coronary Occlusion, Science, 10.1126/science.7466402, 211:4489, (1439-1441), Online publication date: 27-Mar-1981. Cairns J and Klassen G (1981) Intravenous Propranolol Therapy for Acute Myocardial Infarction in Man, Chest, 10.1378/chest.79.3.277, 79:3, (277-285), Online publication date: 1-Mar-1981. Bussmann W, Passek D, Seidel W and Kaltenbach M (1981) Reduction of CK and CK-MB indexes of infarct size by intravenous nitroglycerin., Circulation, 63:3, (615-622), Online publication date: 1-Mar-1981. Ryan W, Karliner J, Gilpin E, Covell J, DeLuca M and Ross J (1981) The creatine kinase curve area and peak creatine kinase after acute myocardial infarction: Usefulness and limitations, American Heart Journal, 10.1016/0002-8703(81)90660-8, 101:2, (162-168), Online publication date: 1-Feb-1981. Afonskaya N, Ostrogorskii Y, Cherpachenko N, Rozonov Y, Kaverina N and Ruda M (1981) Effect of nitroglycerin on the size of an experimental myocardial infarct, Bulletin of Experimental Biology and Medicine, 10.1007/BF00835395, 91:2, (158-160), Online publication date: 1-Feb-1981. KARLSBERG R (1981) Modification of Myocardial Infarct Size by Drugs: Methods for Measuring Infarct Size and Approach to Patient Care Cardiac Pharmacology, 10.1016/B978-0-12-752050-6.50022-8, (415-440), . Vik-Mo H, Mjøs O, Riemersma R and Oliver M (1981) IMPORTANCE OF ISCHEMIA-INDUCED MYOCARDIAL LIPOLYSIS IN DOGS Cardiovascular Physiology: Heart, Peripheral Circulation and Methodology, 10.1016/B978-0-08-026820-0.50018-4, (121-128), . Rackley C, Russell R, Mantle J, Rogers W and Papapietro S (1981) Modern approach to myocardial infarction: Determination of prognosis and therapy, American Heart Journal, 10.1016/0002-8703(81)90386-0, 101:1, (75-85), Online publication date: 1-Jan-1981. Hjalmarson Å (1981) Myocardial Infarction and Beta-Adrenoceptor Blockade Catecholamines and the Heart, 10.1007/978-3-642-68321-3_27, (289-303), . Schuster E and Bulkley B (1980) Ischemia at a distance after acute myocardial infarction: a cause of early postinfarction angina., Circulation, 62:3, (509-515), Online publication date: 1-Sep-1980. Chapelle J, Albert A, Heusghem C, Smeets J and Kulbertus H (1980) Predictive value of serum enzyme determinations in acute myocardial infarction, Clinica Chimica Acta, 10.1016/0009-8981(80)90371-X, 106:1, (29-38), Online publication date: 1-Sep-1980. Ceceña-Seldner F and Villarreal J (2016) Effect of the Kallikrein Inhibitor Aprotinin on Myocardial Ischemia and Necrosis in Man, Angiology, 10.1177/000331978003100708, 31:7, (488-496), Online publication date: 1-Jul-1980. Patterson R and Kirk E (1980) Apparent improvement in canine collateral myocardial blood flow during vasodilation depends on criteria used to identify ischemic myocardium., Circulation Research, 47:1, (108-116), Online publication date: 1-Jul-1980.Apstein C and Ogilby J (1980) Effects of "paradoxical" systolic fiber stretch on ischemic myocardial contracture, compliance, and contractility in the rabbit., Circulation Research, 46:6, (745-754), Online publication date: 1-Jun-1980.Boden W, Liang C and Hood W (1980) Postextrasystolic potentiation of regional mechanical performance during prolonged myocardial ischemia in the dog., Circulation, 61:6, (1063-1070), Online publication date: 1-Jun-1980. Hamby R and Aintablian A (2013) Preload reduction with right ventricular pacing: Effects on left ventricular hemodynamics and contractile pattern, Clinical Cardiology, 10.1002/clc.4960030303, 3:3, (169-177), Online publication date: 1-Jun-1980. Amsterdam E, Banas J, Criley J, Loeb H, Mueller H, Willerson J, Mason D, Beanlands H, Broder M, Ellestad M, Ende M, Forwand S, Hagan A, Lavine P, Messer J, Morch J, Nivatpumin T, Obeid A, Perlstein E, Rahimtoola S, Rapaport E, Schatz I, Schroeder J, Smith S, Towne W and Tuttle W (1980) Clinical assessment of external pressure circulatory assistance in acute myocardial infarction, The American Journal of Cardiology, 10.1016/0002-9149(80)90658-X, 45:2, (349-356), Online publication date: 1-Feb-1980. Vanderbroucke A, Cairns J, Missirlis E and Gauldie J (2006) Radioimmunoassay for Dog Myoglobin, Journal of Immunoassay, 10.1080/01971528008055787, 1:2, (251-269), Online publication date: 1-Jan-1980. Hearse D (1980) Protection of the Ischaemic Myocardium Lactate, 10.1007/978-3-642-67525-6_28, (230-246), . Wilhelmsen L (1980) Long-Term Intervention with Beta-Blocking Agents in Ischemic Heart Disease Selected Topics in Exercise Cardiology and Rehabilitation, 10.1007/978-1-4684-3854-3_11, (145-153), . Ramanathan K, Bodenheimer M, Banka V and Helfant R (1979) Severity of contraction abnormalities after acute myocardial infarction in man: response to nitroglycerin., Circulation, 60:6, (1230-1237), Online publication date: 1-Dec-1979. Woo K and Norris R (2008) Bundle Branch Block after Myocardial Infarction-A Long Term Follow-up*, Australian and New Zealand Journal of Medicine, 10.1111/j.1445-5994.1979.tb04169.x, 9:4, (411-416), Online publication date: 1-Aug-1979. Meltzer R, Woythaler J, Buda A, Griffin J, Harrison W, Martin R, Harrison D and Popp R (1979) Two dimensional echocardiographic quantification of infarct size alteration by pharmacologic agents, The American Journal of Cardiology, 10.1016/0002-9149(79)90314-X, 44:2, (257-262), Online publication date: 1-Aug-1979. Venkatakrishnan R, Leung J, Mason D and Wikman-Coffelt J (1979) Liposomes for the transport of an impermeable fluorescent dye into muscle fibers, Biochemical Medicine, 10.1016/0006-2944(79)90074-7, 21:2, (209-214), Online publication date: 1-Apr-1979. Lakier J, Khaja F and Stein P (1979) Rationale and use of vasodilators in the management of congestive heart failure, American Heart Journal, 10.1016/0002-8703(79)90402-2, 97:4, (519-526), Online publication date: 1-Apr-1979. Bussmann W, Berghof E, Wagner P, Klepzig H and Kaltenbach M (1979) IX. Randomisierte Studie zur Wirkung von Nitroglycerin auf die CK- und CK-MB-Infarktgr��e. Vorl�ufige ErgebnisseIX. Randomized study of the effect of nitroglycerin on CK and CK-MB infarct size. Preliminary report, Klinische Wochenschrift, 10.1007/BF01476564, 57:7, (341-349), Online publication date: 1-Apr-1979. Rentrop K, Blanke H, Karsch K and Kreuzer H (2013) Initial experience with transluminal recanalization of the recently occluded infarct-related coronary artery in acute myocardial infarction - Comparison with conventionally treated patients, Clinical Cardiology, 10.1002/clc.4960020203, 2:2, (92-105), Online publication date: 1-Apr-1979. Kordenat R and Kezdi P (1979) Serotonin blockade during experimental coronary thrombosis, American Heart Journal, 10.1016/0002-8703(79)90432-0, 97:3, (329-338), Online publication date: 1-Mar-1979. Suga H (1979) Minimal oxygen consumption and optimal contractility of the heart: Theoretical approach to principle of physiological control of contractility, Bulletin of Mathematical Biology, 10.1007/BF02460874, 41:2, (139-150), Online publication date: 1-Mar-1979. Thompson P (2008) Limitation of Myocardial Infarct Size: Review of Experimental Basis and Clinical Trials, Australian and New Zealand Journal of Medicine, 10.1111/j.1445-5994.1979.tb04120.x, 9:1, (78-84), Online publication date: 1-Feb-1979. Heikkilä J and Nieminen M (2009) Rapid monitoring of regional myocardial ischaemia with echocardiography and ST segment shifts in man, Acta Medica Scandinavica, 10.1111/j.0954-6820.1979.tb00701.x, 205:S623, (71-95) Ström S (2009) Prognostic Significance of Cardiopulmonary Bypass Time and Postoperative Serum Enzyme Levels in Coronary Surgery, Scandinavian Journal of Thoracic and Cardiovascular Surgery, 10.3109/14017437909100979, 13:2, (133-138), Online publication date: 1-Jan-1979. Selwyn A, Welman E, Fox K, Horlock P, Pratt T and Klein M (1979) The effects of nifedipine on acute experimental myocardial ischemia and infarction in dogs., Circulation Research, 44:1, (16-23), Online publication date: 1-Jan-1979.Richeson J, Akiyama T and Schenk E (1978) A solid angle analysis of the epicardial ischemic TQ-ST deflection in the pig. A theoretical and experimental study., Circulation Research, 43:6, (879-888), Online publication date: 1-Dec-1978. Harken A, Barlow C, Harden W and Chance B (1978) Two and three dimensional display of myocardial ischemic "border zone" in dogs, The American Journal of Cardiology, 10.1016/0002-9149(78)90681-1, 42:6, (954-959), Online publication date: 1-Dec-1978. Pichler M (2013) Noninvasive assessment of segmental left ventricular wall motion: Its clinical relevance in detection of ischemia, Clinical Cardiology, 10.1002/clc.4960010308, 1:3, (173-191), Online publication date: 1-Dec-1978. Selwyn A, Fox K, Welman E, Jonathan A and Shillingford J (1978) Electrocardiographic precordial mapping in anterior myocardial infarction. The critical period for interventions as exemplified by methylprednisolone., Circulation, 58:5, (892-897), Online publication date: 1-Nov-1978. Banka V, Bodenheimer M, Ramanathan K, Hermann G and Helfant R (1978) Progressive transmural electrographic, myocardial potassium ion/sodium ion ratio and ultrastructural changes as a function of time after acute coronary occlusion, The American Journal of Cardiology, 10.1016/0002-9149(78)90938-4, 42:3, (429-443), Online publication date: 1-Sep-1978. Mason D (1978) Afterload reduction and cardiac performance, The American Journal of Medicine, 10.1016/0002-9343(78)90700-3, 65:1, (106-125), Online publication date: 1-Jul-1978. Hardarson T, Henning H, O'Rourke R, Karliner J, Ryan W and Ross J (1978) Variability, reproducibility, and applications of precordial ST-segment mapping following acute myocardial infarction., Circulation, 57:6, (1096-1103), Online publication date: 1-Jun-1978. Hashimoto K, Hamamoto H, Honda Y, Hirose M, Furukawa S and Kimura E (1978) Changes in components of kinin system and hemodynamics in acute myocardial infarction, American Heart Journal, 10.1016/0002-8703(78)90304-6, 95:5, (619-626), Online publication date: 1-May-1978. KU D and Lucchesi B (1978) Effects of dimethyl propranolol (UM-272; SC-27761) on myocardial ischemic injury in the canine heart after temporary coronary artery occlusion., Circulation, 57:3, (541-548), Online publication date: 1-Mar-1978. Apps M and Tinker J (1978) The measurement and cotrrol of myocardial infarct size, Intensive Care Medicine, 10.1007/BF01683132, 4:1, (21-27), Online publication date: 1-Mar-1978. Helfant R, Banka V and Bodenheimer M (1978) Perplexities and complexities concerning the myocardial infarction border zone and its salvage, The American Journal of Cardiology, 10.1016/0002-9149(78)90178-9, 41:2, (345-347), Online publication date: 1-Feb-1978. Hirzel H and Kirk E (1977) The effect of mannitol following permanent coronary occlusion., Circulation, 56:6, (1006-1015), Online publication date: 1-Dec-1977.Hirzel H, Sonnenblick E and Kirk E (1977) Absence of a lateral border zone of intermediate creatine phosphokinase depletion surrounding a central infarct 24 hours after acute coronary occlusion in the dog., Circulation Research, 41:5, (673-683), Online publication date: 1-Nov-1977. Boor P and Reynolds E (1977) Myocardial infarct size: Clinicopathologic agreement and discordance, Human Pathology, 10.1016/S0046-8177(77)80097-X, 8:6, (685-695), Online publication date: 1-Nov-1977. Hearse D, Opie L, Katzeff I, Lubbe W, Van Der Werff T, Peisach M and Boulle G (1977) Characterization of the "border zone" in acute regional ischemia in the dog, The American Journal of Cardiology, 10.1016/0002-9149(77)90187-4, 40:5, (716-726), Online publication date: 1-Nov-1977. Diaz P, Fishbein M, Davis M, Askenazi J and Maroko P (1977) Effect of the kallikrein inhibitor aprotinin on myocardial ischemic injury after coronary occlusion in the dog, The American Journal of Cardiology, 10.1016/0002-9149(77)90069-8, 40:4, (541-549), Online publication date: 1-Oct-1977. Askenazi J, Maroko P, Lesch M and Braunwald E (1977) Usefulness of ST segment elevations as predictors of electrocardiographic signs of necrosis in patients with acute myocardial infarction., Heart, 10.1136/hrt.39.7.764, 39:7, (764-770), Online publication date: 1-Jul-1977. Vik-Mo H (2009) Effects of Acute Myocardial Ischaemia on Platelet Aggregation in the Coronary Sinus and Aorta in Dogs, Scandinavian Journal of Haematology, 10.1111/j.1600-0609.1977.tb02720.x, 19:1, (68-74) Surawicz B (1977) The disputed S-T segment mapping: Is the technique ready for wide application in practice?, The American Journal of Cardiology, 10.1016/0002-9149(77)90112-6, 40:1, (137-140), Online publication date: 1-Jul-1977. Holland R and Brooks H (1977) TQ-ST segment mapping: Critical review and analysis of current concepts, The American Journal of Cardiology, 10.1016/0002-9149(77)90109-6, 40:1, (110-129), Online publication date: 1-Jul-1977. Johnson B and Kucich U (1977) Interrelation between Two Anticomplement Cobra Venom Factors Isolated from Crude Naja naja Cobra Venom, Journal of Pharmaceutical Sciences, 10.1002/jps.2600660711, 66:7, (947-949), Online publication date: 1-Jul-1977. Irvin R and Cobb F (1977) Relationship between epicardial ST-segment elevation, regional myocardial blood flow, and extent of myocardial infarction in awake dogs., Circulation, 55:6, (825-832), Online publication date: 1-Jun-1977. Madias J and Hood W (1977) Precordial ST-segment mapping 3. Stability of maps in the early phase of acute myocardial infarction, American Heart Journal, 10.1016/S0002-8703(77)80011-2, 93:5, (603-609), Online publication date: 1-May-1977. Maroko P, Hillis L, Muller J, Tavazzi L, Heyndrickx G, Ray M, Chiariello M, Distante A, Askenazi J, Salerno J, Carpentier J, Reshetnaya N, Radvany P, Libby P, Raabe D, Chazov E, Bobba P and Braunwald E (1977) Favorable Effects of Hyaluronidase on Electrocardiographic Evidence of Necrosis in Patients with Acute Myocardial Infarction, New England Journal of Medicine, 10.1056/NEJM197704212961603, 296:16, (898-903), Online publication date: 21-Apr-1977. O'Rourke M (1977) ARTERIAL COUNTERPULSATION IN THE MANAGEMENT OF ISCHAEMIC HEART DISEASE, ANZ Journal of Surgery, 10.1111/j.1445-2197.1977.tb03929.x, 47:1, (21-26), Online publication date: 1-Feb-1977. Forrester J, Diamond G and Swan H (1977) Correlative classification of clinical and hemodynamic function after acute myocardial infarction, The American Journal of Cardiology, 10.1016/S0002-9149(77)80182-3, 39:2, (137-145), Online publication date: 1-Feb-1977. Vik-Mo H and Mjoøs O (2009) Effect of sodium salicylate and acetylsalicylic acid on epicardial ST-segment elevation during coronary artery occlusion in dogs, Scandinavian Journal of Clinical and Laboratory Investigation, 10.3109/00365517709092631, 37:4, (287-294), Online publication date: 1-Jan-1977. Vik-Mo H (2011) Distribution of coronary blood flow during acute coronary occlusion in dogs. Effect of nicotinic acid and sodium salicylate, Scandinavian Journal of Clinical and Laboratory Investigation, 10.1080/00365517709101851, 37:8, (697-703), Online publication date: 1-Jan-1977. (1977) Prognosis in Myocardial Infarction, The Lancet, 10.1016/S0140-6736(77)91772-X, 309:8004, (179-180), Online publication date: 1-Jan-1977. Gillespie T, Ambos H, Sobel B and Roberts R (1977) Effects of dobutamine in patients with acute myocardial infarction, The American Journal of Cardiology, 10.1016/S0002-9149(77)80170-7, 39:4, (588-594), . Bussmann W, Löhner J and Kaltenbach M (1977) Orally administered isosorbide dinitrate in patients with and without left ventricular failure due to acute myocardial infarction, The American Journal of Cardiology, 10.1016/S0002-9149(77)80017-9, 39:1, (91-96), . Swan H (1977) Lessons from the Myocardial Infarction Research Units Atherosclerosis, 10.1007/978-1-4613-4220-5_91, (376-379), . Forrester J, Diamond G, Chatterjee K and Swan H (1976) Medical Therapy of Acute Myocardial Infarction by Application of Hemodynamic Subsets, New England Journal of Medicine, 10.1056/NEJM197612162952505, 295:25, (1404-1413), Online publication date: 16-Dec-1976. Hearse D, Stewart D and Braimbridge M (1976) Myocardial protection during bypass and arrest, The Journal of Thoracic and Cardiovascular Surgery, 10.1016/S0022-5223(19)40006-8, 72:6, (880-884), Online publication date: 1-Dec-1976. Awan N, Amsterdam E, Vera Z, DeMaria A, Miller R and Mason D (1976) Reduction of ischemic injury by sublingual nitroglycerin in patients with acute myocardial infarction., Circulation, 54:5, (761-765), Online publication date: 1-Nov-1976.Hillis L, Askenazi J, Braunwald E, Radvany P, Muller J, Fishbein M and Maroko P (1976) Use of changes in the epicardial QRS complex to assess interventions which modify the extent of myocardial necrosis following coronary artery occlusion., Circulation, 54:4, (591-598), Online publication date: 1-Oct-1976. Thompson P and Katavatis V (1976) Acute myocardial infarction. Evaluation of praecordial ST segment mapping., Heart, 10.1136/hrt.38.10.1020, 38:10, (1020-1024), Online publication date: 1-Oct-1976. (1976) PENTAZOCINE IN MYOCARDIAL INFARCTION, The Lancet, 10.1016/S0140-6736(76)90546-8, 308:7991, (888-889), Online publication date: 1-Oct-1976. Madias J and Hood W (1976) Nontransmural Myocardial Infarction, Chest, 10.1378/chest.70.1.2, 70:1, (2-3), Online publication date: 1-Jul-1976. da Luz P, Weil M and Shubin H (1976) Current concepts on mechanisms and treatment of cardiogenic shock, American Heart Journal, 10.1016/S0002-8703(76)80409-7, 92:1, (103-113), Online publication date: 1-Jul-1976. Rivas F, Cobb F, Bache R and Greenfield J (1976) Relationship between blood flow to ischemic regions and extent of myocardial infarction. Serial measurement of blood flow to ischemic regions in dogs., Circulation Research, 38:5, (439-447), Online publication date: 1-May-1976. Adams D, Hessel S, Judy P, Stein J and Abrams H (1976) Differing Attenuation Coefficients of Normal and Infarcted Myocardium, Science, 10.1126/science.1257780, 192:4238, (467-469), Online publication date: 30-Apr-1976. Fox A, Hoffstein S and Weissmann G (1976) Lysosomal mechanisms in production of tissue damage during myocardial ischemia and the effects of treatment with steroids, American Heart Journal, 10.1016/S0002-8703(76)80226-8, 91:3, (394-397), Online publication date: 1-Mar-1976. J. Saliba M, W. Covell J and M. Bloor C (1976) Effects of heparin in large doses on the extent of myocardial ischemia after acute coronary occlusion in the dog, The American Journal of Cardiology, 10.1016/0002-9149(76)90401-X, 37:4, (599-604), Online publication date: 1-Mar-1976. Bodenheimer M, Banka V, Levites R and Helfant R (1976) Temporal relation of epicardial electrographic, contractile and biochemical changes after acute coronary occlusion and reperfusion, The American Journal of Cardiology, 10.1016/0002-9149(76)90386-6, 37:4, (486-492), Online publication date: 1-Mar-1976. Swan H, Blackburn H, DeSanctis R, Frommer P, Hurst J, Paul O, Rapaport E, Wallace A and Weinberg S (1976) Duration of hospitalization in "uncomplicated completed acute myocardial infarction", The American Journal of Cardiology, 10.1016/0002-9149(76)90292-7, 37:3, (413-419), Online publication date: 1-Mar-1976. Hjalmarson Å and Waldenström A (2009) THE IMPORTANCE OF MECHANICAL PERFORMANCE FOR DEVELOPMENT OF MYOCARDIAL INFARCTION IN MAN*, Acta Medica Scandinavica, 10.1111/j.0954-6820.1976.tb05885.x, 199:S587, (221-229) Waagstein F and Hjalmarson Å (2009) EFFECT OF CARDIOSELECTIVE BETA-BLOCKADE ON HEART FUNCTION AND CHEST PAIN IN ACUTE MYOCARDIAL INFARCTION*, Acta Medica Scandinavica, 10.1111/j.0954-6820.1976.tb05881.x, 199:S587, (193-200) Limbourg P, Just H and Lang K (1976) Left ventricular function after acute myocardial infarction, European Journal of Intensive Care Medicine, 10.1007/BF00571890, 2:1, (7-11), . Evans R (2016) Cardiogenic shock, Postgraduate Medicine, 10.1080/00325481.1975.11714223, 58:7, (79-85), Online publication date: 1-Dec-1975. Hood W (1975) "Dynamite Pills" in the Coronary-Care Unit?, New England Journal of Medicine, 10.1056/NEJM197511132932010, 293:20, (1040-1041), Online publication date: 13-Nov-1975. Cohen L and Ross A (2016) Long-Term Management of Complicated Myocardial Infarction, Postgraduate Medicine, 10.1080/00325481.1975.11714026, 57:5, (17-21), Online publication date: 1-Apr-1975. Clarkson R, Tucker H and Wale J (1975) Chapter 6. β-Adrenergic Blocking Agents , 10.1016/S0065-7743(08)60994-X, (51-60), . Braunwald E (1974) Reduction of Myocardial-Infarct Size, New England Journal of Medicine, 10.1056/NEJM197409052911010, 291:10, (525-526), Online publication date: 5-Sep-1974. August 1, 1974Vol 50, Issue 2 Advertisement Article InformationMetrics © 1974 American Heart Association, Inc.https://doi.org/10.1161/01.CIR.50.2.206 Originally publishedAugust 1, 1974 PDF download Advertisement
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