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Conjugate addition of amines to (Rs)-10-isobornyl vinyl sulfoxides

1989; Elsevier BV; Volume: 45; Issue: 22 Linguagem: Inglês

10.1016/s0040-4020(01)89169-9

1464-5416

Stephen G. Pyne, Peter Bloem, Renate Griffith,

Chemical Reaction Mechanisms

Chiral (E) and (Z) (Rs)10-Isobornyl vinyl sulfoxides have been prepared; the (Z) isomers undergo highly diastereoselective conjugate addition with benzylamine whereas the (E) isomers show poor product diastereoselection.