Reduction D′α,α′-dibromoorthoxylenes par les sels chromeux : generation facile d'orthoquino-dimethanes
1984; Elsevier BV; Volume: 25; Issue: 49 Linguagem: Inglês
10.1016/s0040-4039(01)91403-0
ISSN1873-3581
AutoresD. Stephan, Alain Gorgues, A. LE COQ,
Tópico(s)Synthesis of Organic Compounds
Resumoα,α′-Dibromoorthoxylenes undergo a very fast reductive elimination on treatment with chromous chloride, affording the reactive intermediate orthoquinodimethanes which evolve into spiroorthoxylylenes 2 or may be trapped with dienophiles (adducts 3 and 4). Some attempts in the field of anthracycline precursors are reported.
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