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Laser surface modification of polymers to improve biocompatibility: HEMA grafted PDMS, in vitro assay—III

1999; Elsevier BV; Volume: 55; Issue: 5-6 Linguagem: Inglês

10.1016/s0969-806x(99)00212-1

1879-0895

Mohammad Taghi Khorasani, Hamid Mirzadeh, Peter G. Sammes,

Surface Modification and Superhydrophobicity

Polydimethylsiloxane (PDMS) surface modifications were carried out using CO2-pulsed laser, without photosensitizer at ambient condition, to introduce peroxide groups onto the PDMS surface. Such peroxides were capable of initiating graft polymerization of 2-hydroxyethyl methacrylate (HEMA) onto the PDMS. The modified surfaces were characterized using a variety of techniques including scanning electron microscopy (SEM), attenuated total reflectance infrared (ATR-FTIR) and the water drop contact angle measurements. Data from in vitro assays indicated a significant reduction of the platelet adhesion and aggregation for the modified surfaces.