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Reliability of random fecal α1-antitrypsin determination on nondried stools

1986; Elsevier BV; Volume: 109; Issue: 3 Linguagem: Inglês

10.1016/s0022-3476(86)80128-7

1097-6833

Carlo Catassi, Elia Cardinali, G. D’Angelo, Giovanni V. Coppa, P. L. Giorgi,

Streptococcal Infections and Treatments

Several studies have shown that the determination of fecal az-antitrypsin is a valuable indicator of intestinal protein loss. l Compared with conventional techniques for the diagnosis of protein-losing enteropathy, such as the 5tCrlabeled albumin excretion test, the measurement of FA1-AT has the advantage of being safe, nonisotopic, and easily done. Until now, most authors have determined FA-1-AT on lyophilized stools following the technique described by Crossley and Elliot. 2 We evaluated the validity of FA1-AT measurement on nondried rather than lyophilized stools, and report the results of FA-1-AT determination on nondried specimens from a large group of children with various intestinal diseases.