Asymmetric total synthesis of optically active α-curcumene
1979; Elsevier BV; Volume: 20; Issue: 23 Linguagem: Inglês
10.1016/s0040-4039(01)86288-2
ISSN1873-3581
AutoresKohei Tamao, Tamio Hayashi, Hiroshi Matsumoto, H Yamamoto, Makoto Kumada,
Tópico(s)Asymmetric Synthesis and Catalysis
Resumo(R)-(−)-α-Curcumene has been prepared in 66% optical yield and in 34% overall yield in five steps by means of asymmetric Grignard cross-coupling reaction catalyzed by a nickel complex of chiral (aminoalkylferrocenyl)phosphine as a key carbon-carbon bond forming step.
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