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Infective endocarditis in elderly: An Italian prospective multi-center observational study

2014; Elsevier BV; Volume: 177; Issue: 2 Linguagem: Inglês

10.1016/j.ijcard.2014.09.184

1874-1754

Matteo Bassetti, Sergio Venturini, Massimo Crapis, Filippo Ansaldi, Andrea Orsi, Alessio Della Mattia, Gianfranco Sinagra, Bruno Pinamonti, G Rellini, Valentino Moretti, Paolo Bordin, Paolo Giorgi Rossi, Isabella Schiavon, Alessandro Proclemer, Ugolino Livi, Pierluigi Viale, Anna Beltrame, Rita Piazza, Grazia Fazio, V Di Piazza, Mario Maschio,

Cardiac Valve Diseases and Treatments

The epidemiology of infective endocarditis (IE) has changed worldwide over the past half-century [ [1] Slipczuk L. Codolosa J.N. Devila C.D. et al. Infective endocarditis epidemiology over five decades: a systemic review. PLoS ONE. 2013; 8: e82665 Crossref PubMed Scopus (312) Google Scholar ]. In particular, patient age and male predominance have increased over time together with the rates of staphylococcal and enterococcal IE, while the rates of EI due to viridans streptococci have decreased. These changes have important implications for the modern management of IE [ [2] Thuny F. Grisoli D. Collart F. Habib G. Raoult D. Management of infective endocarditis: challenges and perspectives. Lancet. 2012; 379: 965-975 Abstract Full Text Full Text PDF PubMed Scopus (327) Google Scholar ]. Several international and Italian studies have shown an increase in elderly and chronically ill patients with IE [ 1 Slipczuk L. Codolosa J.N. Devila C.D. et al. Infective endocarditis epidemiology over five decades: a systemic review. PLoS ONE. 2013; 8: e82665 Crossref PubMed Scopus (312) Google Scholar , 3 Raymond W.S. Kritharides L. Health care exposure and age in infective endocarditis: results of a contemporary population-based profile of 1536 patients in Australia. Eur Heart J. 2010; 31: 1890-1897 Crossref PubMed Scopus (165) Google Scholar , 4 Leone S. Ravasio V. Durante-Mangoni E. Crapis M. Carosi G. Scotton P.G. et al. Epidemiology, characteristics, and outcome of infective endocarditis in Italy: the Italian Study on Endocarditis. Infection. 2012; 40: 527-535 Crossref PubMed Scopus (134) Google Scholar , 5 Ferrarsi L. Milazzo L. Ricaboni D. Mazzali C. Orlando G. Rizzardini G. et al. Profile of infective endocarditis observed from 2003–2010 in a single center in Italy. BMC Infect Dis. 2013; 13: 545 Crossref PubMed Scopus (33) Google Scholar , 6 Chirillo F. Scotton P. Rocco F. Rigoli R. Borsatto F. Pedrocco A. et al. Management strategies and outcome for prosthetic valve endocarditis. Am J Cardiol. 2013; 112: 1177-1181 Abstract Full Text Full Text PDF PubMed Scopus (21) Google Scholar , 7 Rizzi M. Ravasio V. Carobbio A. Mattucci I. Crapis M. Stellini R. et al. Predicting the occurrence of embolic events: an analysis of 1456 episodes of infective endocarditis from the Italian study on endocarditis (SEI). BMC Infect Dis. 2014; 14: 230 Crossref PubMed Scopus (62) Google Scholar ].