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Serum Mutant K‐ras in the Colorectal Adenoma‐to‐Carcinoma Sequence: Implications for Diagnosis, Postoperative Follow‐up, and Early Detection of Recurrent Disease

2000; Wiley; Volume: 906; Issue: 1 Linguagem: Inglês

10.1111/j.1749-6632.2000.tb06586.x

1749-6632

Barbara M. Ryan, Ross McManus, Jacqueline S. Daly, P. W. N. Keeling, D. G. Weir, François Lefort, Dermot Kelleher,

Genetic factors in colorectal cancer

Annals of the New York Academy of SciencesVolume 906, Issue 1 p. 29-30 Serum Mutant K-ras in the Colorectal Adenoma-to-Carcinoma Sequence: Implications for Diagnosis, Postoperative Follow-up, and Early Detection of Recurrent Disease B. M. RYAN, Corresponding Author B. M. RYAN Department of Clinical Medicine, St. Jamesís Hospital and Trinity College, Dublin 8, Irelanda Fax: +353 1 4730737. [email protected]Search for more papers by this authorR. O. McMANUS, R. O. McMANUS Department of Clinical Medicine, St. Jamesís Hospital and Trinity College, Dublin 8, IrelandSearch for more papers by this authorJ. S. DALY, J. S. DALY Department of Clinical Medicine, St. Jamesís Hospital and Trinity College, Dublin 8, IrelandSearch for more papers by this authorP. W. N. KEELING, P. W. N. KEELING Department of Clinical Medicine, St. Jamesís Hospital and Trinity College, Dublin 8, IrelandSearch for more papers by this authorD. G. WEIR, D. G. WEIR Department of Clinical Medicine, St. Jamesís Hospital and Trinity College, Dublin 8, IrelandSearch for more papers by this authorF. LEFORT, F. LEFORT Department of Clinical Medicine, St. Jamesís Hospital and Trinity College, Dublin 8, IrelandSearch for more papers by this authorD. KELLEHER, D. KELLEHER Department of Clinical Medicine, St. Jamesís Hospital and Trinity College, Dublin 8, IrelandSearch for more papers by this author B. M. RYAN, Corresponding Author B. M. RYAN Department of Clinical Medicine, St. Jamesís Hospital and Trinity College, Dublin 8, Irelanda Fax: +353 1 4730737. [email protected]Search for more papers by this authorR. O. McMANUS, R. O. McMANUS Department of Clinical Medicine, St. Jamesís Hospital and Trinity College, Dublin 8, IrelandSearch for more papers by this authorJ. S. DALY, J. S. DALY Department of Clinical Medicine, St. Jamesís Hospital and Trinity College, Dublin 8, IrelandSearch for more papers by this authorP. W. N. KEELING, P. W. N. KEELING Department of Clinical Medicine, St. Jamesís Hospital and Trinity College, Dublin 8, IrelandSearch for more papers by this authorD. G. WEIR, D. G. WEIR Department of Clinical Medicine, St. Jamesís Hospital and Trinity College, Dublin 8, IrelandSearch for more papers by this authorF. LEFORT, F. LEFORT Department of Clinical Medicine, St. Jamesís Hospital and Trinity College, Dublin 8, IrelandSearch for more papers by this authorD. KELLEHER, D. KELLEHER Department of Clinical Medicine, St. Jamesís Hospital and Trinity College, Dublin 8, IrelandSearch for more papers by this author First published: 25 January 2006 https://doi.org/10.1111/j.1749-6632.2000.tb06586.xCitations: 11Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. REFERENCES 1 Bos, J., S. Fearon, E. Hamilton, M. Verlaan-de-Vries, J. van Boom, A. van der Eb & B. Vogelstein. 1987. Prevalence of ras mutations in human colorectal cancers. Nature 327: 293–297. 10.1038/327293a0 CASPubMedWeb of Science®Google Scholar 2 Anker, P., F. Lefort, V. Vasioukhin, J. Lyautey, C. Lederrey, X.Q. Chen, M. Stroun, H. Mulcahy & M. Farthing. 1997. K-ras mutations are found in DNA extracted from the plasma of patients with colorectal cancer. Gastroenterology 112: 1114–1120. 10.1016/S0016-5085(97)70121-5 CASPubMedWeb of Science®Google Scholar 3 de Kok, J., W. van Solinge, T. Ruers, R. Roelofs, G. van Muijen, J. Williams & D. Swinkel. 1997. Detection of tumour DNA in serum of colorectal cancer patients. Scand. J. Clin. Lab. Invest. 57: 601–604. 10.3109/00365519709055283 PubMedWeb of Science®Google Scholar 4 Kopreski, M., F. Benko, C. Kwee, K. Leitzel, E. Eskander, A. Lipton & C. Gocke. 1997. Detection of mutant K-ras DNA in plasma or serum of patients with colorectal cancer. Br. J. Cancer 76: 1293–1299. 10.1038/bjc.1997.551 CASPubMedWeb of Science®Google Scholar Citing Literature Volume906, Issue1CIRCULATING NUCLEIC ACIDS IN PLASMA OR SERUMApril 2000Pages 29-30 ReferencesRelatedInformation