Decrease of plasma somatostatin‐like immunoreactivity and increase of gastrin and insulin levels in peripheral venous blood of conscious dogs following infusions of pentagastrin. The possible role of vagal “gastrinergic” fibres as inhibitors of gastrointestinal somatostatin release

1982; Wiley; Volume: 115; Issue: 1 Linguagem: Inglês

10.1111/j.1748-1716.1982.tb07052.x

ISSN

1365-201X

Autores

Kerstin Uvnäs‐Moberg,

Tópico(s)

Pancreatic function and diabetes

Resumo

Somatostatin has been shown to exert inhibitory actions on gastric acid secretion, gastrointestinal motility and on the release of gastrointestinal and pancreatic hormones. Furthermore, somatostatin is produced and stored in endocrine cells in the corporeal and antral parts of the stomach and in the pancreas, indicating that endogenous somatostatin might take part in the control of gastrointestinal and pancreatic functions. (For a review on the subjects see Efendic, Luft & Uvnäs‐Wallensten 1982.)

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