Portal de Periódicos da CAPES

Etiopathogenesis of Behcet's disease

2009; Elsevier BV; Volume: 9; Issue: 4 Linguagem: Inglês

10.1016/j.autrev.2009.10.005

1873-0183

Claudia Mendoza‐Pinto, Mario Garcı́a-Carrasco, Mario Jiménez-Hernández, César Jiménez, Carlos Riebeling‐Navarro, Arnulfo Hernán Nava-Zavala, Mauricio Vera Recabarren, Gerard Espinosa, Javier Jara Quezada, Ricard Cervera,

Retinal and Optic Conditions

Bechet's disease (BD) is an inflammatory, multi systemic disease with spontaneous remissions and relapses similar to various autoimmune diseases. BD leads to organ damage, including the eyes, skin, joints, etc., which produces various clinical manifestations. The central histopathologic characteristic is systemic vasculitis with perivascular inflammatory infiltrates. The etiopathogenesis is unknown, although immunological abnormalities, possibly induced by susceptible microbiological pathogens, have been postulated.