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Results from pelvic exenteration for locally advanced colorectal cancer with lymph node metastases

1998; Lippincott Williams & Wilkins; Volume: 41; Issue: 2 Linguagem: Inglês

10.1007/bf02238243

1530-0358

Jin‐ichi Hida, Masayuki Yasutomi, Takamasa Maruyama, Akihiro Nakajima, Toshihiro Uchida, Tsukasa Wakano, Tadao Tokoro, Kiyoshige Fujimoto,

Colorectal Cancer Treatments and Studies

PURPOSE: We examined the survival benefit of pelvic exenteration for locally advanced colorectal cancer with lymph node metastases, because this issue remains controversial. METHODS: Medical records of 50 patients who underwent curative pelvic exenteration for colorectal cancer were reviewed retrospectively. Nodal metastases were examined by the clearing method in 29 patients and by the conventional manual method in 21 patients. RESULTS: Invasion to contiguous pelvic organs was present in 40 patients (80 percent) and absent in 10 patients (20 percent). Node metastases were present in 33 patients (66 percent). Operative morbidity and mortality rates were 22 percent (11 patients) and 6 percent (3 patients), respectively. Respective five-year survival rates were 60 and 80 percent in the groups with and without organ invasion (no significant difference). Five-year survival rates in patients with nodal metastases was 54.6 percent but was significantly higher, 82.4 percent, in patients without nodal metastases. Five-year survival in 28 patients with both organ invasion and nodal metastases was 53.6 percent. CONCLUSIONS: Long-term survival was afforded by pelvic exenteration for locally advanced colorectal cancer with nodal metastases.