Electroanalysis of pM-levels of urokinase plasminogen activator in serum by phosphorothioated RNA aptamer
2015; Royal Society of Chemistry; Volume: 140; Issue: 11 Linguagem: Inglês
10.1039/c4an02354d
ISSN1364-5528
AutoresMarta Jarczewska, László Kékedy‐Nagy, Jesper S. Nielsen, Rui Campos, Jørgen Kjems, Elżbieta Malinowska, Elena E. Ferapontova,
Tópico(s)Biosensors and Analytical Detection
ResumoElectrochemical assay for the universal biomarker of several cancers, urokinase plasminogen activator, uPA, based on uPA-specific fluorinated RNA aptamer and methylene blue redox indicator, allows 1 pM uPA analysis in serum, making it practically useful for clinical applications.
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