EFFECTS OF 17α-HYDROXY-6α-METHYLPROGESTERONE ACETATE (DEPO-PROVERA) ON URINARY GONADOTROPHINS AND OESTROGENS IN MAN
1963; Oxford University Press; Volume: 44; Issue: 1 Linguagem: Inglês
10.1530/acta.0.0440075
ISSN1479-683X
AutoresZvi Laron, G. Rumney, Rat L, Nazar Ahmed Naji,
Tópico(s)Hormonal and reproductive studies
ResumoABSTRACT Weekly injections of 17α-hydroxy-6α-methylprogesterone acetate to three patients with gonadal dysgenesis exhibiting high urinary gonadotrophins and one girl with marked enlargement of breasts and high urinary oestrogens, led to suppression of both urinary gonadotrophins and oestrogens in two patients and of oestrogens alone in the third case. There was no significant effect on the urinary 17-ketosteroids or 17-hydroxycorticosteroids.
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