Luffariellolide, an anti-inflammatory sesterterpene from the marine spongeLuffariella sp.
1987; Birkhäuser; Volume: 43; Issue: 8 Linguagem: Inglês
10.1007/bf01951682
ISSN0014-4754
AutoresK. F. ALBIZATI, Theodore R. Holman, D. John Faulkner, Keith B. Glaser, Robert S. Jacobs,
Tópico(s)Microbial Natural Products and Biosynthesis
ResumoLuffariellolide (2) is a sesterterpene from the Palauan spongeLuffariella sp. that has useful anti-inflammatory properties. In contrast with the irreversible action of manoalide (1) on phospholipase A2, luffariellolide (2) is a slightly less potent but partially reversible PLA2 inhibitor.
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