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5-(4-Chlorophenyl)-4-methyl-3-(1-(2- phenylethyl)piperidin-4-yl)isoxazole: A Potent, Selective Antagonist at Human Cloned Dopamine D4 Receptors

1996; American Chemical Society; Volume: 39; Issue: 10 Linguagem: Inglês

10.1021/jm960072u

1520-4804

Michael Rowley, Howard B. Broughton, Ian Collins, Raymond Baker, Frances Emms, Rosemarie Marwood, Shil Patel, Smita S. Patel, C I Ragan, Stephen B. Freedman, Paul D. Leeson,

Parkinson's Disease Mechanisms and Treatments

ADVERTISEMENT RETURN TO ISSUEPREVLetterNEXT5-(4-Chlorophenyl)-4-methyl-3-(1-(2- phenylethyl)piperidin-4-yl)isoxazole: A Potent, Selective Antagonist at Human Cloned Dopamine D4 ReceptorsMichael Rowley, Howard B. Broughton, Ian Collins, Raymond Baker, Frances Emms, Rosemarie Marwood, Shil Patel, Smita Patel, C. Ian Ragan, Stephen B. Freedman, and Paul D. LeesonView Author Information Merck Sharp and Dohme, Neuroscience Research Centre, Terlings Park, Eastwick Road, Harlow, Essex CM20 2QR, U.K. Cite this: J. Med. Chem. 1996, 39, 10, 1943–1945Publication Date (Web):May 10, 1996Publication History Received22 January 1996Published online10 May 1996Published inissue 1 January 1996https://pubs.acs.org/doi/10.1021/jm960072uhttps://doi.org/10.1021/jm960072urapid-communicationACS PublicationsCopyright © 1996 American Chemical SocietyRequest reuse permissionsArticle Views837Altmetric-Citations99LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Amines,Anions,Nitrogen,Receptors,Selectivity Get e-Alerts