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Unexpected severe hepatotoxicity of ciprofloxacine: two case reports

2011; Taylor & Francis; Volume: 34; Issue: 2 Linguagem: Inglês

10.3109/01480545.2010.495392

1525-6014

Cabir Alan, Hasan Koçoğlu, Ahmet Reşit Ersay, Yunus Ertung, Hasan Kurt,

Pharmacological Effects and Toxicity Studies

Ciprofloxacin is a fluoroquinolone antibiotic that has a relatively low rate of occurence of adverse side effects. However, increasing evidences suggest that ciprofloxacin may cause unexpected severe liver damage. Especially, the risk of hepatotoxicity is significantly higher in elderly men receiving drug for a long time. In this article, 2 cases of unexpected severe hepatoxicity of ciprofloxacin are presented.