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Unresectable Primary Tumor of Head and Neck: Does Neck Dissection Combined With Chemoradiotherapy Improve Survival?

2001; Lippincott Williams & Wilkins; Volume: 12; Issue: 5 Linguagem: Inglês

10.1097/00001665-200109000-00007

1536-3732

Francesco Carinci, Lazzaro Cassano, Antonio Farina, Stefano Pelucchi, C Calearo, Vincenzo Modugno, Ingrid Nielsen, P. Api, Antonio Luigi Pastore,

Tumors and Oncological Cases

A study regarding patients with primary and previously untreated advanced histologically proven squamous cell carcinoma of the head and neck was performed to compare two treatment modalities: neck dissection followed by chemoradiotherapy (Group I) versus chemoradiotherapy alone (Group II). Fifty-four patients were randomly chosen to receive Group I or II treatment. Our results demonstrate that Group I treatment has a higher and statistically significant disease-specific survival rate. We suggest that an association of neck dissection plus chemoradiotherapy can be useful in the event of unresectable advanced carcinomas.