Portal de Periódicos da CAPES

Hornet Stings Presenting to a Primary Care Hospital in Anuradhapura District, Sri Lanka

2014; Elsevier BV; Volume: 25; Issue: 1 Linguagem: Inglês

10.1016/j.wem.2013.09.012

1545-1534

Buddhika Wijerathne, Geetha K Rathnayake, Suneth Agampodi,

Rabies epidemiology and control

Hymenopterid stings and consequent allergic reactions are common indications for emergency medical care visits and a substantial public health issue globally.1Diaz J.H. Hymenopterid bites, stings, allergic reactions, and the impact of hurricanes on hymenopterid-inflicted injuries.J La State Med Soc. 2007; 159: 149-157PubMed Google Scholar, 2Forrester J.A. Holstege C.P. Forrester J.D. Fatalities from venomous and nonvenomous animals in the United States (1999–2007).Wilderness Environ Med. 2012; 23: 146-152PubMed Scopus (40) Google Scholar Multiple hornet stings can sometimes lead to fatal anaphylaxis and fatal multiple organ failure.3Watemberg N. Weizman Z. Shahak E. Aviram M. Maor E. Fatal multiple organ failure following massive hornet stings.J Toxicol Clin Toxicol. 1995; 33: 471-474Crossref PubMed Scopus (32) Google Scholar Sri Lanka, being a tropical country, has a large assortment of forests from wet montane rain forests to tropical dry mixed evergreen forests.4The National Atlas of Sri Lanka. 2nd ed. Sri Lanka: Department of Survey; 2007.Google Scholar Anuradhapura is the largest district of Sri Lanka situated in the dry zone, and most of the area is covered with tropical dry mixed evergreen forests, with a mean annual rainfall ranging from 1250 to 1500 mm.4The National Atlas of Sri Lanka. 2nd ed. Sri Lanka: Department of Survey; 2007.Google Scholar The average temperature fluctuates between 29° and 38°C. The district is predominantly rural, and the residing population often lives in close proximity to the wildlife.4The National Atlas of Sri Lanka. 2nd ed. Sri Lanka: Department of Survey; 2007.Google Scholar The lesser-banded hornet Vespa affinis (Figure, A), the black-bellied hornet Vespa basalis, the Asian giant hornet Vespa mandarinia, and the greater-banded hornet Vespa tropica are the documented species of hornets found in Sri Lanka.5Bingham C.T. Hymenoptera: wasps and bees.in: The Fauna of British India: Including Ceylon and Burma. Vol. 1. Taylor & Francis, London1897Google Scholar All these species are a distinct genus (Vespa) of social wasps. Among them, Vespa mandarinia is the largest hornet capable of injecting the greatest amount of venom and is responsible for many of the systemic reactions. With the restoration of peace after 30 years of civil war and the resumption of historical agricultural practices including deforestation to support chena cultivation techniques, the growing population of the predominantly agricultural district of Anuradhapura identified hornet stings as an emerging environmental hazard for agricultural workers and others. The objectives of this retrospective report were to describe the demographics, presenting clinical manifestations, and outcomes of human hornet sting cases admitted to a rural, regional hospital in Anuradhapura during a 1-year observation period. We conducted a hospital-based prospective study from October 2011 to September 2012 in a divisional hospital in Tammannawa, a primary-care hospital (PCH) close to more than 20 farming communities (1244 admissions and 16,128 outpatient visits during the year 2011). The study area is located at latitude 8.37° N and longitude 80.59° E. All consecutive patients admitted to the PCH with a history of hornet sting, who recognized the insect as a hornet and gave informed written consent, were included in the study. During the recruitment procedure, photographs of the abovementioned hornet species were shown to sting victims, and the characteristics of their colony (Figure, B, C) were obtained to exclude misidentification with other common species of hymenopterans such as the bees (giant honeybee Apis dorsata, dwarf honeybee Apis florae, and honeybee Apis cerana indica) and paper wasp, which are also common in this study setting. An interviewer-administered questionnaire was used to obtain demographic details, exposure factors, and clinical characteristics. A detailed clinical examination was conducted by the first author (in-charge medical officer at the hospital during the study), and all abnormal findings were recorded. Of the 811 total admissions to the hospital during the study period, 78 (9.6%) were attributable to hornet stings, which included 51 (65.4%) males and 27 (34.6%) females. The mean age of the population was 37 years (SD, 13 years), with the majority (46.2%) belonging to the 30- to 45-year-old age group (Table 1). More than half of the study participants (n = 40, 51.3%) were farmers. Most of the cases (n = 40, 51.3%) of hornet stings were reported from June to August. Stings occurred mostly in paddy fields or chena cultivations (n = 35 [male 29, female 6], 44.9%) and during farming activities (n = 28 [males 23, females 5], 35.9%).Table 1Demographic details and circumstance of the stingVariableSingle stingMultiple stingsn%n%Demographic characteristic Educational attainment Secondary level or above006785.9 Postprimary level or less22.6911.5 Occupation Agriculture004051.3 Housewife001620.5 Student11.3911.5 Other/unemployed11.31114.1Circumstances of the sting Location of sting event Indoors22.667.7 Near water resource00.067.7 Paddy field/chena cultivation00.03544.9 Backyard00.01215.4 Road00.01114.1 Forest00.067.7 Activity at the time of sting Walking00.01012.8 Working00.03038.5 Farming00.02835.9 Resting/sleeping22.6810.3 Time of sting Morning (6:00 am–11:59 am)11.34253.8 Day (noon–5:59 pm)11.33342.3 Evening (6:00 pm–11:59 pm)00.011.3 Open table in a new tab One third (34.6%) of the victims presented to the hospital within an hour, another 34.6% presented within 1 to 6 hours, and the remainder delayed for more than 6 hours before coming to the hospital. Only 59% of people tried first aid, of which 37.2% tried home remedies (applying vinegar, juices of lime or onion) and 21.8% tried Ayurvedic medicines (applying a paste made from herbal plants including Murraya koenigii and Desmodium triflorum). Pain (n = 77, 98.7%), swelling (n = 75, 96.2%), and fright (sudden intense fear of threat to life; n = 61, 78.2%) were the most common clinical features observed (Table 2). Systemic signs were rare. The upper limb was the most commonly stung part of the body.Table 2Signs, symptoms, and site of hornet stingVariableSingle stingMultiple stingsn%n%Signs and symptoms Pain at the local site22.67596.2 Swelling at the local site22.67596.2 Fright11.36076.9 Difficulty in breathing00.067.7 Difficulty in swallowing00.033.8 Oliguria00.022.6 Vomiting00.011.3Site of sting Head and neck006583.3 Upper limb11.36684.6 Trunk002835.9 Lower limb11.3911.5 Open table in a new tab Five victims (6.4%) had developed anaphylaxis. All of them were treated with intramuscular adrenaline 0.5 mL (1:1000), intravenous chlorpheniramine 10 mg, and intravenous hydrocortisone 200 mg. All 5 victims had multiple stings ranging 12 to 16 all over the body. All of them reached the hospital within less than 1 hour of the sting. Of the 5 victims, 2 were agricultural workers and another 2 were housewives. After stabilizing, they were transferred to a tertiary-care unit for further investigation and tertiary care. There was no sting-related deaths during this period. As this is the only healthcare facility available in the area, we admitted all the sting victims and kept them under observation for possible complications. Forty-six (59%) of sting victims had 24 to 48 hours of hospital stay. Eight (10.3%) sting victims left against medical advice even though the possible complications (anaphylaxis, renal failure, cardiac arrhythmias) were explained to them. On account of unbearable pain and fright, 71.8% sought medical care, whereas 25.6% sought care because of others’ advice to seek medical care. Only 2.6% of victims knew the potential complications of sting and sought medical care. Thirty-four victims identified the hornet species as the lesser banded hornet Vespa affinis with the help of photographs and details of the colony and size of insects. The rest of the victims identified the insect only as a species of Vespa, but they were convinced that the insect was not a bee (giant honeybee Apis dorsata, dwarf honeybee Apis florae, honeybee Apis cerana indica) or paper wasp. Sri Lanka is experiencing an increasing number of health events associated with rapid deforestation and disturbances to the ecological system. Elephant attacks and snakebites on humans are well known in Sri Lanka for their lethal outcomes. Giant honeybee stings also have gained attention during the past few years. However, hornet stings have not been described as an environmental health hazard probably because they are presented mostly to PCHs in rural areas, where scientific reporting is not in practice. The present paper from a small PCH shows that hornet stings accounted for 9.6% of hospital admissions during a year, showing a much greater healthcare burden than one might have expected. Hornets, unlike bees, can sting multiple times and can be induced to swarm and attack in waves on exposure to pheromones. They do not die after stinging as seen in bees because their stingers are not barbed and are not pulled out of their bodies. A majority of the stings we observed were in agricultural workers who got stung while they were working in paddy fields near the forest or performing chena cultivation. (Chena involves the clearing of either primitive or second-growth jungle land every year for cultivation on a rotational basis, which is associated with rapid deforestation.) Stings among women were associated with collecting firewood for energy in the backyard or forest. The highest incidence of stings occurred in August, which is the time hornets tend to increase their colony size. August is also the time where chena cultivators clear forest areas for their work, putting humans in close contacts with a hornet. Several studies have shown that prognosis of hymenopterid sting victims depends on the number of stings and the duration to reach the hospital after a sting.6Vetter R.S. Visscher P.K. Camazine S. Mass envenomations by honey bees and wasps.West J Med. 1999; 170: 223-237PubMed Google Scholar We observed that only 34.6% of sting victims reached the hospital in less than 1 hour. The key reason for the delay was attempting first aid methods. This lack of knowledge and delay in seeking care might lead to severe anaphylaxis reactions. Only 6.4% of victims required admission to tertiary-care hospitals with laboratory facilities and patient monitoring devices available. It is vital to identify sting victims who need rapid emergency care by primary-care providers to control and manage possibly fatal reactions. This work shows that knowledge about the management of hornet stings (and other probable stings and bites) is crucial in the primary-care setting, which is not usually addressed in undergraduate training in tertiary-care hospitals. One of the limitation of this study was the lack of data on previous history of a systemic reaction to hornet, wasp, or bee sting, which is a serious risk factor for developing anaphylaxis with a second sting.2Forrester J.A. Holstege C.P. Forrester J.D. Fatalities from venomous and nonvenomous animals in the United States (1999–2007).Wilderness Environ Med. 2012; 23: 146-152PubMed Scopus (40) Google Scholar This study is based on observations from a single hospital. A multicenter study would provide a complete epidemiological profile of hornet stings in Sri Lanka. In conclusion, this study shows that the burden of hornet stings in rural Sri Lankan settings could be as large as 9.6% of total admissions and the anaphylaxis reactions to hornet stings are not rare. Proper training of primary healthcare physicians on managing anaphylaxis and availability of emergency drugs are essential in this setting to prevent life-threatening situations.