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BIBTEX RIS

Duffy and duffy-related human antigens in primates

1984; Elsevier BV; Volume: 13; Issue: 2 Linguagem: Inglês

10.1016/s0047-2484(84)80061-5

1095-8606

Marcos Palatnik, Arthur W. Rowe,

Virus-based gene therapy research

Duffy-related Fy3, Fy5, and Fs antigens on red cells of various species of primates were characterized and compared to the findings of others. While most species appear to be monomorphic for the Fy b and Fy 3 antigens, Macaca mulatta, Macaca fascicularis , and Pan troglodytes are polymorphic for Fy b with the gene frequencies ranging for Fy b from 0.72 to 0.80 and for Fy from 0.20 to 0.28. It may be postulated that Fy:3 and Fy(a-b-) could constitute the oldest phenotypes common to several species in primate evolution, while Fy5 and Fy a appear to be more recent antigens particular to the gorilla and human lineages respectively.