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Inclusion of l-glucose within the specificity limits of the active sugar transport system of hamster small intestine

1968; Elsevier BV; Volume: 163; Issue: 3 Linguagem: Inglês

10.1016/0005-2736(68)90124-7

1879-2642

Wolfgang F. Caspary, Robert K. Crane,

Digestive system and related health

Incubation in vitro of segments and everted sacs of hamster small intestine have been used to study the mode of absorption of l-glucose. By all current criteria, l-glucose is a substrate of the intestinal transport system for d-glucose. We have examined accumulation against a concentration gradient, substrate inhibition, phlorizin sensitivity, Na+ dependence, energy dependence and counterflow. The estimated Km value for l-glucose is 65 mM.