Observations on THE RELATION OF MALIGNANT DISEASE TO BENIGN TUMOURS OF THE INTESTINAL TRACT
1929; BMJ; Volume: 2; Issue: 3586 Linguagem: Inglês
10.1136/bmj.2.3586.567
ISSN0959-8138
Autores Tópico(s)Metastasis and carcinoma case studies
ResumoTH2_E subject of our discussioni is not iew,.but it is one to wlhiel considerable attentioni has beeii devoted in recent yenars, and it may bo uiseful if, at this time, we enldeavour to br-ing together suLlch facts as we may think awe have aisccrtained in the course of our labours, and such specula- tions as may help to give a clue to ouir obscurities.In ])articular it is desirable to know to wlhat extent we are in agreemlet oni tlhe maini issues, and whereinl individual experience differs.Lu goinig over the data, anatomical and documentary, which I liave accumulated on this subject during the last itenty years, I have been surlprised at both its amount and its variety.Simple tumours of the alinmontary tract, like .oimianiy other uniobtrusiv-e lesions, are found with con- a;iderable frequency when carefully looked for, and, while usually of little clinical importance per se, in a certain proportion of cases they are attended by the most serious consequences.It is with one of these consequences, the development of malignancy, that we are concernied to-day.As openier of the discussion it will probably be most coniv-eniient if I pass in rev-iew the varlious kinids of simple tiliiiours which occur in the alimentalry tr-act, considering at the same time the incidence and nature of thle malignant thlitniges to which each i.s liable.Subsequent speakers can then extend anid elaborate those aspects of the problem in wh-lieli they are particularly interested.Mv owni remarks will be based chiefly oni my personal experience of human material, but it is hoped that duiring the discussion the comiparative and experimental sides will not be i1eglected.CONNECTiVvJ TIsSUE TTmuounIs.Simple colnnective tissuie tumours of the alimentary tract aire of comparatively infrequenit occulrrenice, the onily two of any consequence beinig lipoma and leiomyyoma.I have encounitered only five examples of submucous lipoma of the stomachl, all of them small and sessile, lllere casual findings at necropsy.In another case there was a pedunculated lipooma the size of a hazel-nut at the junction of the first aniid seconid portions of the duodenum.It also was a casual findlinig; but tumours of this type elsewhere in the intes-
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