Artigo Revisado por pares

Evolution in the Palladium‐Catalyzed Cross‐Coupling of sp‐ and sp 2 ‐Hybridized Carbon Atoms

2003; Wiley; Volume: 42; Issue: 14 Linguagem: Inglês

10.1002/anie.200201617

ISSN

1521-3773

Autores

Rik R. Tykwinski,

Tópico(s)

Sulfur-Based Synthesis Techniques

Resumo

Palladium-catalyzed bond-formation between alkynes and aryl halides and triflates is as fascinating today as it was nearly 30 years ago when such reactions were introduced by Sonogashira (see scheme; OTf=CF3SO3). More facile procedures, new acetylide coupling partners, and more efficient catalysts and ligand systems all combine to expand the limits of this versatile reaction.

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