Artigo Revisado por pares

The biuret reaction: Changes in the ultraviolet absorption spectra and its application to the determination of peptide bonds

1962; Elsevier BV; Volume: 3; Issue: 1 Linguagem: Inglês

10.1016/0003-2697(62)90042-8

ISSN

1096-0309

Autores

George L. Ellman,

Tópico(s)

Chemical Synthesis and Analysis

Resumo

A modification of the biuret reaction utilizing changes in the ultraviolet spectrum accompanying the reaction has been presented. The method is sensitive to concentrations of as low as 0.01 mg/ml protein, i.e., 10–15 times as sensitive as the visible biuret reaction. A survey of the specificity of the reaction is included.

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