Portal de Periódicos da CAPES

How to achieve rapid separations in counter-current chromatography

2006; Elsevier BV; Volume: 1114; Issue: 1 Linguagem: Inglês

10.1016/j.chroma.2006.02.019

1873-3778

Lijuan Chen, Ian Sutherland,

Ginseng Biological Effects and Applications

A new generation of high performance coil planet centrifuges is now making it possible to realize the enormous potential of liquid-liquid partition chromatography for the rapid and predictable scale up of separation processes. This paper uses a separation of flavonoids to demonstrate how rapid fractionations can be obtained at high flow rates with limited loss of resolution and with significant increase in throughput. Furthermore, it is shown that chromatograms at various flows can be modeled so that optimum conditions can be rapidly assessed.