
Whole-Body 99mTc-Octreotide Scintigraphy With SPECT/CT to Detect Occult Tumor Inducing Paraneoplastic Osteomalacia
2014; Lippincott Williams & Wilkins; Volume: 40; Issue: 1 Linguagem: Inglês
10.1097/rlu.0000000000000341
ISSN1536-0229
AutoresNapoleão Ramalho Rodrigues, Ana Luísa Calich, Maurício Etchebehere, Wilson André Ichiki, Fabio Payão Pereira, Elaine Maria Ingrid Amstalden, Elba Etchebehere,
Tópico(s)Cancer Diagnosis and Treatment
ResumoA 32-year-old woman presented with progressive myalgia, bone pain, fatigue, insufficiency hip fractures, high urine phosphate, and low serum phosphate and vitamin D levels. These findings were suggestive of oncogenic osteomalacia. A whole-body 99mTc-octreotide scintigraphy with SPECT/CT showed uptake on a sclerotic intramedullary lesion in the left medial tibia plateau. MRI depicted a solid lesion. The lesion was surgically removed; the patient became asymptomatic, and follow-up laboratory results normalized. Histopathologic examination revealed a vascular hemangiopericytoma-like tumor, positive for somatostatin receptor (SSR-2). Whole-body 99mTc-octreotide scintigraphy with SPECT/CT may detect occult oncogenic osteomalacia tumors.
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