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Revisão Revisado por pares
BIBTEX RIS

Pathogenesis of Non-Hodgkin's Lymphoma

2011; Lippincott Williams & Wilkins; Volume: 29; Issue: 14 Linguagem: Inglês

10.1200/jco.2010.33.3252

ISSN

1527-7755

Autores

Hendrik Nogai, Bernd Dörken, Georg Lenz,

Tópico(s)

Viral-associated cancers and disorders

Resumo

The understanding of the molecular pathogenesis of non-Hodgkin's lymphomas (NHL) has significantly improved in recent years. Advances in molecular biology and genetics lead to the identification and characterization of several oncogenic pathways involved in lymphomagenesis. This knowledge will ultimately lead to improved diagnostic and therapeutic strategies for patients with NHL. This review summarizes current concepts of the molecular pathogenesis of the most common NHL subtypes, with a special emphasis on diffuse large B-cell lymphoma, the most common lymphoma subtype.

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