Hemoglobin Etobicoke: α84(F5) serine replaced by arginine

1969; Canadian Science Publishing; Volume: 47; Issue: 2 Linguagem: Inglês

10.1139/o69-023

ISSN

0008-4018

Autores

J. H. Crookston, Helen A. Farquharson, D. Beale, H. Lehmann,

Tópico(s)

Hemoglobin structure and function

Resumo

In a Canadian family of northern Irish origin, a new hemoglobin variant, hemoglobin Etobicoke, was observed. It differs from hemoglobin A by having a residue of arginine in place of serine in position 84 of the α-chain (helical notation F5). This hemoglobin is slightly less stable than hemoglobin A, but it does not cause an inclusion body anemia.

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