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Clostridium difficile infection

2014; UNIVERSIDADE DE SÃO PAULO; Volume: 4; Issue: 2 Linguagem: Inglês

10.4322/acr.2014.015

2236-1960

Stephen A. Geller, Fernando Peixoto Ferraz de Campos,

Viral gastroenteritis research and epidemiology

Clostridium difficile infection (CDI) is a significant and increasing medical problem, surpassing methicillinresistant Staphylococcus aureus as the most common hospital-onset or facility-associated infection, 1-3 and a key element in the challenging battle against hospitalacquired infections.This Gram-positive, anaerobic, spore-forming colonizes the intestinal tract after antibiotics have altered the normal intestinal flora.CDI may be life-threatening; the death rate has dramatically increased from 3,000 per year in 1999-2000 to 14,000 per year in 2006-2007. 4 The use of antibiotics, although not the only risk factor, is the most significant triggering event, increasing in incidence with prolonged antibiotic use. 2,3,5[8] However, not all cases of CDI are associated with Image in focus Imagem em foco Clostridium difficile infection