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Striato-nigral degeneration and shy-drager syndrome (idiopathic orthostatic hypotension)

1975; Elsevier BV; Volume: 78; Issue: 3 Linguagem: Inglês

10.1016/s0303-8467(75)80049-7

1872-6968

O. Vuia,

Parkinson's Disease Mechanisms and Treatments

The present paper reports on a case which evolved clinically with a Parkinson syndrome and attacks of orthostatic hypotension. Dystrophic lesions were found in the substantia nigra, putamen and autonomic bulbo-medullary axis. This case demonstrates that striato-nigral degeneration of the Adams, van Bogaert and van der Eecken type and the Shy-Drager syndrome (orthostatic hypotension with neurologic syndrome) are part of the same pathologic entity representing nervous multisystem degeneration developing in the presenium.