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BIBTEX RIS

3‐Oxo‐12α‐hydroxyfriedelane from Maytenus gonoclada : structure elucidation by 1 H and 13 C chemical shift assignments and 2D‐NMR spectroscopy

2007; Wiley; Volume: 45; Issue: 10 Linguagem: Inglês

10.1002/mrc.2062

ISSN

1097-458X

Autores

Mauro Lúcio Gonçalves de Oliveira, Lucienir Pains Duarte, Grácia Divina F. Silva, Sidney Augusto Vieira Filho, Vagner Fernandes Knupp, Fernando Gomes P. Alves,

Tópico(s)

Biological Activity of Diterpenoids and Biflavonoids

Resumo

Abstract The compounds 3‐oxofriedelane (1), 3β‐hydroxyfriedelane (2), 3,11‐dioxofriedelane (3), 3,16‐dioxofrie delane (4) and 3‐oxo‐12α‐hydroxyfriedelane (5) were isolated from the hexane extract of Maytenus gonoclada Mart. ( Celastraceae ) leaves. Structural formula and the stereochemistry of the new pentacyclic triterpene 3‐oxo‐12α‐hydroxyfriedelane (5) were established through 1 H and 13 C NMR and DEPT 135 spectral data including 2D experiments (HMBC, HMQC, COSY, and NOESY) and mass spectrometry (GC‐MS). Copyright © 2007 John Wiley & Sons, Ltd.

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