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JUGULAR BULB CREATINE KINASE AS AN INDICATION OF SLIGHT TRANSIENT BRAIN DAMAGE

1967; Elsevier BV; Volume: 290; Issue: 7510 Linguagem: Inglês

10.1016/s0140-6736(67)90113-4

1474-547X

L. Langton, C. P. Moxon, D Riddoch, Ruth Westhead, A. L. Woolf,

Acute Ischemic Stroke Management

The creatine-kinase (C.P.K.) level in blood taken from a peripheral vein may be greatly raised in cases with necrotic gliomas, cerebral ischaemia, or anoxia, especially after status epilepticus. The jugular bulb serum C.P.K. may be raised above that of the arterial or limb vein blood serum while still remaining within the normal range. Too few cases showing this arteriovenous difference have so far been encountered to determine how transient they are or whether they indicate structural lesions of the type mentioned above. Where the jugular bulb is sought with a needle to which suction is applied through a syringe, first samples should be disregarded since aspiration of muscle tissue into the needle may cause misleading increases in the C.P.K. level of the blood obtained.